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ChipCare’s handheld analyzer attracts one of Canada’s largest-ever healthcare angel investments

Device could significantly improve HIV diagnostics in developing world

Chipcare CorporationOTTAWA, September 16, 2013 — An innovative, handheld point-of-care analyzer, developed by ChipCare Corporation, has secured one of the largest ever angel investments in Canada’s healthcare sector.

Phase II financing has closed, with an investment of $2.05M to support ChipCare’s continuing development and commercialization over the next three years.

Media coverage: Biotechnology Focus, TechVibes, BetaKit, Healthrender, Crunchbase, Toronto Star and VentureLab.

The financing evolved through a uniquely collaborative funding model among Canadian social angel investors, including Maple Leaf Angels, MaRS Innovation and the University of Toronto (Connaught Fund), with special financing leadership from Grand Challenges Canada and the Government of Canada.

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Dr. Hofstein’s Op-Ed for The Hill-Times, “Biotechnology research: A knowledge economy”

This op-ed on Canadian biotechnology and the knowledge economy appeared in The Hill-Times (subscription required), Canada’s politics and government newsweekly, September 9:

Obesity, cancer, heart disease and stroke, diabetes, Parkinson’s disease, Alzheimer’s, or the more general stresses of an aging population: no matter which area of concern holds our collective gaze from moment to moment, improving health outcomes and healthcare is the No. 1 challenge for the world’s economy.

Canada has the holistic approach and translational research necessary to address health care’s pervasive challenges, with particular strengths in biotechnology.

In 2007, the Government of Canada made advancing translational research a top priority through the Science and Technology Strategy, with emphasis on cancer, metabolic disorders and, most recently, neurology, as part of the government’s response to the burdensome realities of neurodegenerative disorders.

Scientific research has made significant progress in unraveling the underlying causes of disorders such as Parkinson’s disease and Alzheimer’s disease, but translating these findings into useful clinical treatments is the key to attaining meaningful accomplishments. Only clinical treatment successes will alleviate pressure on the economy.

Transformational research is the essential first step in this process, but even more importantly, it needs to be put in the hands of those who can translate it into realistic and useful outcomes for patients in particular and society in general.

Thanks to research analytics that capture publications, citations, and other significant metrics, we know Canadian researchers punch above their weight, particularly in medical research. Canada’s challenge is not the quality or quantity of our research ideas but our ability to commercialize those ideas and translate them into market-ready products.

Aware of and concerned by this gap between fundamental basic research and useful patient, social, and economic outcomes, the Canadian government established the Centres of Excellence for Commercialization and Research (CECR) program in 2007. Part of the internationally-recognized Networks of Centres of Excellence suite of programs, the CECR program is a unique collaboration between the three federal granting agencies (the Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council, and Social Sciences and Humanities Research Council), along with Industry Canada, and Health Canada.

Designed to bridge the challenging gap between innovation and commercialization, the CECR program matches clusters of research expertise with the business community to share the knowledge and resources that bring innovations to market faster.

MaRS Innovation was among the first CECRs to be created in 2008, largely based on the founding belief of its members that Toronto is a fertile research land for precisely this kind of translational activity.

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Cellax profiled in SciBX; MaRS Innovation’s MSc PoP program cited in National Post supplement

CellaxThe Cellax technology was profiled in a recent issue of  SciBX (subscription necessary). MaRS Innovation is mentioned in the article as the technology’s commercialization agent.

Here’s an excerpt:

Ontario Institute for Cancer Research scientists have developed glycopolymer-conjugated docetaxel nanoparticles that outperform Abraxane in mouse models of breast cancer. The Ontario Institute for Cancer Research (OICR) is backing the program with $1.5 million to take it to the clinic. The expectation is that the product’s ability to target the tumor stroma rather than the tumor itself will differentiate it from Abraxane and other chemotherapeutic formulations.”

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Call for Applications: MaRS Innovation seeks applicants for early-stage MSc POP projects

Government of Ontario logoMaRS Innovation (MI) seeks applicants for the Medical Sciences Proof-of-Principle (MSc PoP) program, which supports early-stage medical science technologies and allows their founding teams to conduct crucial proof-of-principle work.

Through the two-year MSc POP program, MI will distribute funding awards to qualified applicants within its membership on behalf of the Ministry of Research and Innovation (MRI). Funds are available in $25,000 or $75,000 grants.

“At MaRS Innovation, the PoP program functions as a kind of internal Dragons’ Den,” says Dr. Raphael Hofstein, president and CEO of MaRS Innovation. “For three years, we’ve used a panel of industry leaders to hear pitches from the founding teams of the most promising technologies in our intellectual property pipeline. Based on their assessments, the strongest projects receive PoP funding to fuel their prototyping and other proof-of-principle work.”

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Whirlscape’s Minuum keyboard debuts at #2 on Google’s Top New Paid Apps list

Minuum #2 top paid new Android App on Google Play store
Minuum (icon second from left) is  the #2 Top Paid New Android App on the Google Play store. Graphic courtesy of Whirlscape Inc.

The Minuum keyboard, which made its public debut in the Google Play Store on August 21, 2013, has already reached #2 position in Google’s “Top New Paid Android Apps” list. The keyboard is the only non-game currently in that list’s top 10.

In the “Top Paid in Android Apps” general category, Minuum is already #9. The keyboard, made by Whirlscape Inc., has a four-star rating among users.

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BioDiaspora predicts Hajj and Umrah as two key possible spread points for MERS coronavirus

BioDLogo_whiteBioDiaspora, a start-up company based on the research of company founder, Dr. Kamran Khan of St. Michael’s Hospital, has identified two mass gatherings in the Islamic world as key possible spread points for the life-threatening MERS coronavirus, which emerged in the Middle East in early 2012.

BioDiaspora’s disease-tracking platform, which correlates uses global air traffic patterns to predict the international spread of infectious disease (as described in the original media release from St. Michael’s Hospital):

The first is umrah, a pilgrimage that can be performed at any time of year but is considered particularly auspicious during the month of Ramadan, which this year began on July 9 and ends on Aug. 7. The second is the hajj, a five-day pilgrimage required of all physically and financially able Muslims at least once in their life. It takes place Oct. 13 to 18 this year and is expected to draw more than 3 million people.

Predicted spread of MERS virus based on hajj travel pattters. Source: Potential for the International Spread of Middle East Respiratory Syndrome in Association with Mass Gatherings in Saudi Arabia/PLOS Currents Outbreaks.
Predicted spread of MERS coronavirus based on hajj travel patterns. Source: Potential for the International Spread of Middle East Respiratory Syndrome in Association with Mass Gatherings in Saudi Arabia/PLOS Currents Outbreaks.

It also identified the Mumbai-India corridor as particularly vulnerable to MERS based on the predicted exit traffic of travelers leaving the hajj and returning to their home countries following the mass religious event.

Khan’s research findings, published in PLOS Currents: Outbreaks, have attracted media coverage from the Times of India, CanIndia, Toronto Star‘s Foreign Desk blog (Jennifer Yang), Science Daily.com, DowntoEarth.org and Homeland Security News Wire.

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Bringing mad science to mass production: Financial Post features the Bio Printer project

University of Toronto PhD student Lian Len with a prototype tissue printer. Photo courtesy of Dominic Ali (University of Toronto)
University of Toronto PhD student Lian Len with a prototype tissue printer. Photo courtesy of Dominic Ali (University of Toronto)

“It’s one thing to invent a machine that prints skin, but it’s a whole other challenge to bring what seems like the domain of mad science to mass production,” Matthew Braga wrote in  “Looking for ways to get ‘skin’ in the game,” published in the Financial Post on July 15.

The article focuses on MaRS Innovation’s (MI) and the Innovations and Partnerships Office’s (University of Toronto) joint efforts to commercialize the bio printer, a “prototype 3D printer that, instead of extruding layers of plastic and other inorganic materials into physical shapes, builds layer upon layer of cell-laden tissue, a process that could lead to the cheap, rapid production of human skin.”

Braga’s article was syndicated in the Regina Leader Post, the Saskatoon Star-Phoenix,  and the Vancouver Sun, among other Canadian publications.

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Flybits to demo technology at TD Night It Up! event in Markham

TD Night It Up! bannerLooking for something to do tonight? Come to Markham and see Flybits‘ technology in action.

Starting Friday, July 12 and running until July 14, Flybits Zones have been created for visitors to experience at the TD Night It Up! event in Markham.

The Flybits mobile user interface presents relevant information from surrounding geo-fences (zones).
The Flybits mobile user interface presents relevant information from surrounding geo-fences (zones).

Night It Up! is a outdoor night market styled in the vein of night markets from Taiwan and Hong Kong and many others from across Asia.

As a community partner for the Night It Up! event, Flybits team members will be on hand to interact with visitors and demonstrate the technology.

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Whirlscape’s team on Minuum, Indiegogo and crowdfunding a beta keyboard launch

Every six weeks, MaRS Innovation’s marketing and communications manager writes a guest post for the MaRS Discovery District blog profiling MI’s activities or one of our start-up companies. You can read the original post on the MaRS blog.

Whirlscape logoOn Monday, June 17, Whirlscape Inc. released the beta version of its hotly anticipated, tiny, one-dimensional digital keyboard, Minuum: “the little keyboard for big fingers.”

If you follow tech gadget news, you’ve likely read about or even supported the company’s successful Indiegogo campaign, which raised more than US$87,000—over 870% above their modest initial goal of $10,000—from nearly 10,000 supporters who have now become beta users for the product.

The stats don’t end there. By number of funders, the Minuum Keyboard Project’s campaign is in Indiegogo’s top 10 of all time and is ranked No. 2 among all technology campaigns. Over 1.1 million people worldwide viewed Minuum’s original teaser video on YouTube, which the Whirlscape team edited and shot themselves.

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