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Triphase secures FDA orphan drug designation for Marizomib in Malignant Glioma

MI_triphaseTORONTO and SAN DIEGO (November 19, 2015) — Triphase Accelerator Corporation, a private drug development company dedicated to advancing novel compounds through Phase 2 proof-of-concept, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for marizomib to treat patients with malignant glioma.

Malignant glioma is an aggressive form of brain cancer for which there is a significant unmet need in current treatments due to the disease’s poor prognosis. Triphase is evaluating marizomib, a novel and highly potent proteasome inhibitor, in combination with bevacizumab in patients with recurrent glioblastoma.

Orphan drug designation is granted by the FDA Office of Orphan Products Development (OOPD) to novel drugs or biologics that treat a rare disease or condition affecting fewer than 200,000 patients in the United States.

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BCS’s Bedside PEWS™ covered in Hospital News

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Bedside Clinical Systems and their flagship product, Bedside PEWS™, were featured in the February 2014 issue of Hospital News.

Bedside Clinical Systems‘ (BCS) flagship product, the Bedside Paediatric Warning System or BedSidePEWS, was covered in the February 2014 edition of Hospital News.

The article, written by Rajesh Sharma who is president and CMO of BCS, explains how the technology helps decrease the amount of code blues in paediatric patients.

Invented by Dr. Christopher Parshuram of the Hospital of Sick Children (SickKids), Bedside PEWS™ is now in three hospitals in Canada, the United States and New Zealand. The technology received FDA approval last year.

Here’s an excerpt from the article:

The program digitally logs, charts, and evaluates seven vital sign items thst sre part of routine clinical assessments and then summarizes them into a singly score. From the BedsidePEWS score, care providers can better match the level of care with the patient’s required needs, thereby improving patient outcomes and reducing the number of urgent calls, code blue incidents and related deaths.

“Identifying at-risk patients is significant since approximately 5,000 children in North America experience a code blue event each year, from which too many children die or sustain neurological deficit. BedsidePEWS hopes to improve outcomes for these patients and their families,” says Dr. Parshuram.

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MaRS Innovation Forms Strategic Drug-Development Partnership with NovoTek Therapeutics Inc. in China

ScarX logoMaRS Innovation (MI), The Hospital for Sick Children (SickKids) and NovoTek Therapeutics Inc. (NovoTek)  have announced a strategic partnership to co‐develop, and bring to the Chinese market, a novel therapeutic cream aimed at reducing scar formation post surgery.

This project was covered in The Globe and Mail on May 7, 2012.

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