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WaveCheck campaign part of new study on crowdfunding medical research

MI’s Fazila Seker also interviewed in National Post article on what prompts medical researchers to consider crowdfunding

WavecheckThe WaveCheck crowdfunding campaign, which raised $53,390 on Indiegogo to support clinical trials for a clinical technique invented by researchers at Sunnybrook Health Sciences Centre and Ryerson University, was included in a new Canadian-led study on the merits of crowdfunding to support cancer and rare diseases.

Crowdfunding drug development: The state of play in oncology and rare diseases,” was published in Drug Discovery Today‘s June issue.

MaRS Innovation has confirmed with lead author Professor Nick Dragojlovic of the University of British Columbia that WaveCheck was among the campaigns included in the study.

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WaveCheck breast cancer technology receives $100,000

OICR’s catalyst grant enables WaveCheck to open first partner site at MD Anderson Cancer Center in May

WavecheckTORONTO, April 8, 2014 — People with breast cancer are a step closer to knowing if their tumour is responding to chemotherapy at the start of treatment, thanks to a $100,000 catalyst grant from the Ontario Institute for Cancer Research (OICR).

The funding builds upon MaRS Innovation‘s Indiegogo crowdfunding campaign for WaveCheck, which successfully raised over $50,000 from over 500 supporters worldwide in two months last fall.

Read Jane Gerster’s article for the Toronto Star about OICR’s catalyst grant for WaveCheck. This announcement was also covered in Metro, BetaKit and Council of Academic Hospitals of Ontario’s Catalyst newsletter.

WaveCheck, a clinical technique invented, refined and tested by scientists at Sunnybrook Health Sciences Centre and Ryerson University over 20 years, aims to show whether chemotherapy is actually destroying a breast cancer tumour at the beginning of chemotherapy treatment (in as little as four weeks), rather than at the end of treatment (typically four to six months).

In early clinical testing, WaveCheck’s inexpensive, non-invasive, image-guided technology (shown here) shows promise as an accurate, efficient way to monitor tumour response. Sunnybrook has partnered with GE Healthcare to co-develop WaveCheck as a clinical tool.
In early clinical testing, WaveCheck’s inexpensive, non-invasive, image-guided technology (shown here) shows promise as an accurate, efficient way to monitor tumour response. As of March 2015, Sunnybrook has partnered with GE Healthcare to co-develop WaveCheck as a clinical tool.

In early clinical testing, the non-invasive, image-guided technology has shown promise as an accurate, efficient way to monitor tumour response, opening the door to tailored treatment.

“This is a significant step towards achieving the goal of personalized medicine. The clinical trials will confirm that information provided by WaveCheck can determine if the treatment is the appropriate one or that other options should be chosen, sparing patients the side effects of treatments that will not likely be successful,” said Dr. Tom Hudson, OICR’s president and scientific director. “If successful, WaveCheck could become a standard tool in the cancer treatment of the future.”

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MI’s Rafi Hofstein featured in Biotechnology Focus

Dr. Raphael Hofstein (left), the Honourable Minister Reza Moridi (centre) and Dr. Mark
MI’s Dr. Raphael Hofstein (left), the Honourable Minister Reza Moridi (centre) and Dr. Mark Poznansky of the Ontario Genome Institute on the January 2014 cover of Biotechnology Focus.

In a January 24, 2014 Biotechnology Focus cover article, author Shawn Lawrence discusses MaRS Innovation President and CEO Dr. Raphael (Rafi) Hofstein‘s recent visit to learn more of the emerging science and technology markets in Singapore and Japan.

The trip allowed Hofstein to discuss current MI projects, specifically start-ups XLV Diagnostics Inc. and DVLR Therapeutics Inc., whose products could benefit from Singapore’s proximity to medical technology markets in India and China.

Hofstein joined other delegates from Canada, including Dr. Mark Poznansky, president and CEO of the Ontario Genome Institute (OGI).

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WaveCheck co-directers talk crowdfunding commercialization research on CBC’s “The World This Weekend”

waveMaRS Innovation staff and WaveCheck Campaign Co-directors Dr. Fazila Seker and Elizabeth Monier-Williams spoke with the CBC’s Colleen Ross about the process of crowdfunding WaveCheck’s partner-based clinical studies on “The World This Weekend.”

The radio segment, called “Crowdfunding Science,” aired on January 25, 2014 and discussed the lack of funding researchers have access to for commercialization, making it harder to advance research that could be helping people in a variety of industries.

To listen to the full interview, click here.

WaveCheck’s crowdfunding campaign is an example of how MaRS Innovation gets creative when traditional funding channels take too long or run dry, speeding up the commercialization process.

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Yonge Street Media Highlights MaRS Innovation Bioprinter Project

MI Project Manger Fanny Sie discusses Toronto’s impact on 3D printing landscape

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MaRS Innovation’s Fanny Sie is project manager for the Bioprinter, a 3D printer that can print on organic material.

In a December 4 article, part of a feature series on technology in Toronto, Yonge Street Media reporter Andrew Seale highlights the creative and innovative technological work surrounding the 3D printing and cyber security sectors in the city.

MaRS Innovation’s Fanny Sie is managing business development for the Bioprinter, a 3D printer using University of Toronto technology that’s capable of printing on organic material, including skin.

By printing on skin, the cost of treating burns on the body could be reduced.

Here’s an excerpt from the article (links and emphasis ours):

“Cells are very intelligent, you just have to be able to put them close enough to one another in order for them to take over,” says Sie adding that some of the research is a partnership with the Sunnybrook Health Sciences Centre and Research Institute.

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WaveCheck crowdfunding campaign honours contriburing artists, sponsors and inventors

Reception at Sunnybrook Hospital recognizes WaveCheck’s inventors, contributing artists and the three women featured in the campaign video

The WaveCheck Indiegogo campaign continues to generate wide support from MaRS Innovation’s community. To give back and show their appreciation, the campaign team hosted a reception at Sunnybrook Health Sciences Centre in the Louise Temerty Breast Cancer Centre on November 6, 2013.

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From left, WaveCheck campaign co-director Elizabeth Monier-Williams contributing artist Janet F. Potter, WaveCheck supporter Carmen Tellez O’Mahony, contributing artist Deniz Ergun Seker, WAAC President Dale Butterill and contributing artist Lila Miller.
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WaveCheck’s appreciation event was held at The Louise Temerty Breast Cancer Centre, Sunnybrook Health Sciences Centre.

Present were several members of the Women’s Art Association of Canada (WAAC) who donated 11 of the 15 artworks to the campaign. Also present was Dale Butterill, president of WAAC, who expressed support during her opening remarks. Together with members of WAAC, contributing artists donated over $15,000 worth of art to the campaign.

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WaveCheck raises over $41,000 for breast cancer treatment monitoring in three weeks

waveOver 340 people worldwide have joined WaveCheck‘s Indiegogo crowdfunding campaign to fund a breakthrough clinical technique for breast cancer that promises to revolutionize the way chemotherapy is monitored.

“Breast Cancer Awareness Month’s positivity makes it easy to overlook the fact that 60 to 70 per cent of chemotherapy treatments fail,” says Dr. Gregory Czarnota, chief of Radiation Oncology at Sunnybrook Health Sciences Centre and co-inventor of WaveCheck with Professor Michael C. Kolios of Ryerson University. “WaveCheck’s technology can tell people with breast cancer and their doctors if a particular chemotherapy is working in as little as four weeks.”

WaveCheck’s campaign made the Top 10 list for the most financially successful Canadian crowdfunding campaigns on both Kickstarter and Indiegogo in Globe and Mail’s Report on Small Business. CTV News Channel, CBC Toronto News (see the above clip), CBC Radio Canada and Canadian Healthcare Technology have also covered the project, along with Oshawa Today (radio), The Ryersonian and The Eyeopener.

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WaveCheck to Transform Chemotherapy Monitoring for Women with Breast Cancer

Indiegogo campaign to raise funds for North American clinical study during Breast Cancer Awareness Month; 12 artists donate 13 original works worth over $15,000 to support campaign

Toronto, Canada (October 9, 2013) — WaveCheck a painless, non-surgical clinical technique developed by a Sunnybrook Health Sciences Centre oncologist and a Ryerson University physicist and supported by MaRS Innovation — is poised to transform chemotherapy response monitoring for women with breast cancer.

Dr. Gregory Czarnota of Sunnybrook Health Sciences (left) and Professor Michael Kolios of Ryerson University, WaveCheck's inventors.
Dr. Gregory Czarnota of Sunnybrook Health Sciences (left) and Professor Michael Kolios of Ryerson University, WaveCheck’s inventors.

WaveCheck combines traditional ultrasound with new software to detect responses to chemotherapy in breast cancer tissues. By making better, more accurate information available about a woman’s response to her chemotherapy treatment in weeks rather than months, WaveCheck creates greater transparency through dialogue between a women and her doctors, empowering her to participate in discussions about whether a given chemotherapy treatment is effective.

Contribute to WaveCheck‘s Indiegogo campaign and help make this technology available to all women with breast cancer faster.

Media coverage: CTV News Channel, the Globe and Mail and Canadian Healthcare Technology have covered WaveCheck’s campaign.

Developed by Dr. Gregory Czarnota, chief of Radiation Oncology at Sunnybrook’s Odette Cancer Centre, and Michael C. Kolios, professor of Physics and Canada Research Chair in Biomedical Applications of Ultrasound at Ryerson, WaveCheck has been used in clinical studies with nearly 100 women receiving upfront, neoadjuvant chemotherapy to treat locally-advanced breast cancer. These results are published in two leading journals, Clinical Cancer Research and Translational Oncology.


In the Indiegogo campaign video, Czarnota, Kolios and three of the 100 women who participated in the first Sunnybrook study explain WaveCheck’s impact.

“The hard truth for women with breast cancer is that 60 to 70 per cent of chemotherapy treatments fail,” said Czarnota, who is also a senior scientist and director of cancer research at Sunnybrook Research Institute and assistant professor in the University of Toronto’s Departments of Radiation Oncology and Medical Biophysics within the Faculty of Medicine. “The 1.5 million women worldwide who will be diagnosed with breast cancer this year need to know that their chemotherapy is working as soon as possible. But this kind of treatment monitoring doesn’t currently exist in standard clinical practice. Instead, a woman’s tumour response is evaluated after she completes her chemotherapy treatment, which is typically a four- to six-month process.

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What does MaRS Innovation’s funding extension mean for Toronto’s academic entrepreneurs?

Every six weeks, MaRS Innovation’s marketing and communications manager writes a guest post for the MaRS Discovery District blog profiling MI’s activities or one of our start-up companies. You can read the original post on the MaRS blog.

Created in 2008, MaRS Innovation (MI) bridges the chasm between the early-stage technologies emerging from its 16 member institutions and successful startup companies and licensable technologies.

By offering early-stage funding in tandem with hands-on management, business development, mentorship and intellectual property protection strategy, MI acts as a commercialization agent for its members and researchers.

Networks of Centres of Excellence logoEarlier this year, the Networks of Centres of Excellence of Canada awarded MI $14.95 million to continue its mandate as a Centre of Excellence for Commercialization and Research (CECR), matched by $25 million from membership fees and private sector investments.

So what does that success mean for MI’s ability to serve the needs of academic entrepreneurs based in Toronto?

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