OtoSim Inc.

MaRS Innovation’s top 10 portfolio stories for 2014

December 15, 2014
Susanne Staer
Acquisitions

MaRS Innovation enjoyed an exceptional year in 2014. Our team continues to collaborate with researchers within our membership to help bridge the commercialization gap between their world-leading research and creating successful start-up companies or licenses.

Here are our picks for the top 10 news stories from MaRS Innovation’s portfolio.

1. Triphase Accelerator Corporation, in which MaRS Innovation is an investor, started the year with a bang by signing a collaboration and option agreement with Celgene Corporation. In October, Triphase initiated a Phase I clinical study to evaluate marizomib in Glioblastoma (GBM) with Celgene, signed an agreement to provide Celgene with an option to acquire a new bi-specific antibody (licensed by Triphase from PharmAbcine) and closed the year by announcing that Triphase’s proteasome inhibitor, marizomib, demonstrates potent synergistic anti-multiple myeloma activity in combination with pomalidomide.

2. Flybits Inc., spun out of Ryerson University, announced a $3.75 million Series A financing with Robert Bosch Venture Capital to advance its context-aware mobile experience platform. The company was also named a Red Herring Top 100 North America winner.

3. XLV Diagnostics Inc., spun out from Sunnybrook Health Sciences Centre and the Thunder Bay Regional Research Institute, secured a $3 million Series A investment round with Boston-based Bernard M. Gordon Unitrust. XLV’s product will provide mammography image quality equivalent to top-of-the-line mammography machines currently in use, and will do so at a fraction of the cost of current generation systems. The funding will support continued product development and regulatory approval.

Portfolio Snapshot: Minuum debuts on Google Glass, Crowdmark named most innovative at SIIA

May 14, 2014
Susanne Staer
Awards

There’s been lots of activity in MI’s portfolio this week (and it’s only Wednesday). Read down for what you need to know about Whirlscape, Crowdmark, OtoSim, and ApneaDx.

Whirlscape launches Google Glass demo video

Whirlscape’s Minuum keyboard nabbed a four-star review from CNET’s editors only days before announcing their technology is now available for Google Glass. Watch the UTEST graduate‘s newest demo video.

Reaction coverage: BNN, the Telegraph (U.K.), WPRO (radio), CNET, Mashable, TechCrunch, Mobile Syrup and Android Central, among various other tech blogs.

Crowdmark named “Most Innovative” at SIIA conference

The Education Division of the Software & Information Industry Association (SIIA) showcased some of the newest and most innovative products in the education technology market, and recognized the best among them as part of the Innovation Incubator program at the 13th annual Education Industry Summit, the leading conference for the K-12 and postsecondary education technology market, held May 12-14 at the Palace Hotel in San Francisco.

From their blog:

Crowdmark was named Most Innovative among more than 50 applicants,

Portfolio snapshot: UTEST in the Wall Street Journal, OtoSim & Sylleta win pitch competitions

April 14, 2014
Susanne Staer
Awards

Here's a snapshot of some recent portfolio activity: UTEST, the early-stage technology accelerator MI runs in partnership with the University of Toronto, was cited in the Wall Street Journal as…

OtoSim Inc. and U of T collaboration makes MEdSim Magazine

MEdSim Magazine profiled OtoSim Inc. and their partnership with the University of Toronto to establish a Student Training Fund in otoscopy.

Led by a $200,000 donation by Mr. Ralph Chiodo of Active Green + Ross, OtoSim Inc. provided 66 OtoSim™ simulation units to U of T.

Otoscopy, the diagnostic examination of the ear, is one of the most poorly acquired medical skills in students because traditional methods of study rely on lectures and print material. Using the OtoSim™ simulation unit allows students to interactively improve otoscopy skills before they reach the clinic.

$200,000 donation to establish Student Training Fund in Otoscopy at U of T

OtoSim™ device’s integration into medical students’ curriculum to help improve diagnosis accuracy by 44 per cent

A $200,000 donation led by Mr. Ralph Chiodo of Active Green + Ross will help establish a Student Training Fund in Otoscopy at U of T in partnership with OtoSim Inc.

TORONTO, ON (Feb. 5, 2014) — The University of Toronto (U of T) is creating a Student Training Fund in Otoscopy in partnership with OtoSim Inc., thanks to a $200,000 donation led by Mr. Ralph Chiodo, founder of Active Green + Ross. Other donors include some franchisees of Active Green + Ross and others among Chiodo’s friends and associates.

The Halldale Group, a publisher specializing in simulation and training information, covered this funding announcement.

Through the donation, undergraduate medical students will have access to better otoscopy training through the use of the OtoSim™ in their curriculum. Otoscopy, the diagnostic examination of the ear, is one of the most poorly-acquired medical skills in students, general practitioners and pediatricians, achieving a fifty per cent accuracy rate.

Ralph Chiodo’s donation allows OtoSim Inc. to provide 66 otoscopy training units, known as the OtoSim™, to U of T. The devices, which can be networked to facilitate mass training exercises, will help undergraduate medical students to be effectively trained to diagnose ear problems using an otoscope.

Watch how the OtoSim™ can be used in mass training exercises. Nearly 100 second-year medical students voluntarily attended the OtoSim™ training session to better prepare their otoscopy skills for the clinic.

“We are excited to be the first official OtoSim™ mass-training site and thank Mr. Ralph Chiodo for leading the charge on fundraising for this unique learning opportunity,” said Ian J. Witterick, professor and chair in U of T’s Department of Otolaryngology-Head & Neck Surgery.

“A clinical study demonstrated that with only a couple hours of group training, the accuracy of third-year medical students increased from 54 per cent to 78 per cent,” said Dr. Andrew Sinclair, OtoSim CEO and former senior director at MaRS Innovation. “Mr. Ralph Chiodo’s donation will help us to ensure that more medical students graduate with a much higher proficiency in this critical primary physical examination skill.”

MaRS Innovation’s 2013 Top 10 List

2013 was an exceptional year for MaRS Innovation. Here are the top 10 news stories from our commercialization portfolio. 1. MaRS Innovation secures a $15 million CECR funding extension In January,…

OtoSim CEO on growing a successful start-up company with help from MaRS Innovation

December 18, 2013
Susanne Staer
Media Coverage

Dr. Andrew (Andy) Sinclair, OtoSim’s CEO, was interviewed by PharmaBoadroom.com on October 10, 2013 to discuss the company’s success and plans for the future. OtoSim's otoscopy training device is revolutionizing…

Portfolio Update: OtoSim on Healthy Sim blog; UTEST grads Whirlscape and Crowdmark launch betas

August 21, 2013
Susanne Staer
Crowdmark

Here’s a snapshot of some MI start-up news that you may have missed over the last week: OtoSim Inc.'s medical training simulators, which teach otoscopy and otolargyngology skills in an…

Financial Post profiles OtoSim Inc.’s innovative medical learning device

“If there’s one profession for which you don’t want students to have learning gaps, it’s medicine,” Rebecca Walberg wrote in the Smart Shift: Agenda for Innovation section in the Financial Post on May 7 (reprinted in the Vancouver Sun on May 9 and in the Calgary Herald on June 6, 2013). “Yet that’s exactly what Dr. Paolo Campisi saw while working with medical students at the University of Toronto.”

Walberg’s article, “Innovation in medical learning a Canadian business success story,” describes the process Campisi and his colleague and co-founder Dr. Vito Forte, both of the Hospital for Sick Children and cross-appointed to U of T, undertook to design the OtoSim device, which addresses the gap in how students were learning skills associated with otolaryngology (ear, nose and throat diseases or infections).

Here’s an excerpt (beginning with a quote from Dr. Forte):

“The answer wasn’t more time to lecture or show big pictures on a screen, but rather some kind of instrument that would mimic the experience of looking into an ear with an otoscope. And we went through a number of prototypes developing a simulator that can do just that.”

The result is the OtoSim, brought to market and sold by OtoSim Inc. The simulator consists of a rubber ear made to scale, and a computer display integrated into the model where the eardrum would be in a patient, which can display images of ear canals that correspond to a wide range of medical conditions.

U of T med students participate in mass medical simulation exercise

OtoSim Night revolutionizes how students learn to identify ear pathologies

On Feb. 13, 2013, almost 100 second-year University of Toronto (U of T) medical students participated in an optional, intensive, one-hour otoscopy workshop using the OtoSim™ — a training and simulation system that is radically changing the way students in Canada and around the world learn this poorly-acquired medical skill.

And, if you want to use simulation technology to change the way medical professionals are taught, ear disease is a good place to start.

Additional photos from this event are posted on OtoSim Inc.’s Flickr account. A longer version of the OtoSim Night at U of T video is also available on the company’s YouTube channel.

“Historically, otoscopy simulation involved looking at an image of an eardrum on a piece of film at the end of a rubber ear,” said Dr. Andrew Sinclair, CEO of OtoSim Inc. “OtoSim™ has a digital image bank that is orders of magnitude more extensive. The instructor can electronically point to areas within the image and confirm that the student sees the pathology of interest. Diagnostic accuracy goes up enormously.”

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