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Call for Applications: MaRS Innovation seeks applicants for early-stage MSc POP projects

Government of Ontario logoMaRS Innovation (MI) seeks applicants for the Medical Sciences Proof-of-Principle (MSc PoP) program, which supports early-stage medical science technologies and allows their founding teams to conduct crucial proof-of-principle work.

Through the two-year MSc POP program, MI will distribute funding awards to qualified applicants within its membership on behalf of the Ministry of Research and Innovation (MRI). Funds are available in $25,000 or $75,000 grants.

“At MaRS Innovation, the PoP program functions as a kind of internal Dragons’ Den,” says Dr. Raphael Hofstein, president and CEO of MaRS Innovation. “For three years, we’ve used a panel of industry leaders to hear pitches from the founding teams of the most promising technologies in our intellectual property pipeline. Based on their assessments, the strongest projects receive PoP funding to fuel their prototyping and other proof-of-principle work.”

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Bringing mad science to mass production: Financial Post features the Bio Printer project

University of Toronto PhD student Lian Len with a prototype tissue printer. Photo courtesy of Dominic Ali (University of Toronto)
University of Toronto PhD student Lian Len with a prototype tissue printer. Photo courtesy of Dominic Ali (University of Toronto)

“It’s one thing to invent a machine that prints skin, but it’s a whole other challenge to bring what seems like the domain of mad science to mass production,” Matthew Braga wrote in  “Looking for ways to get ‘skin’ in the game,” published in the Financial Post on July 15.

The article focuses on MaRS Innovation’s (MI) and the Innovations and Partnerships Office’s (University of Toronto) joint efforts to commercialize the bio printer, a “prototype 3D printer that, instead of extruding layers of plastic and other inorganic materials into physical shapes, builds layer upon layer of cell-laden tissue, a process that could lead to the cheap, rapid production of human skin.”

Braga’s article was syndicated in the Regina Leader Post, the Saskatoon Star-Phoenix,  and the Vancouver Sun, among other Canadian publications.

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Dr. Raphael Hofstein’s MRI blog post: How Team Ontario’s biotechnology takes on the world

Dr. Raphael Hofstein
Dr. Raphael Hofstein, president & CEO, MaRS Innovation.

Dr. Raphael (Rafi) Hofstein is president and CEO of MaRS Innovation (MI) – the commercialization agent for an exceptional research discovery pipeline stemming from 16 leading Ontario academic institutions. As a single entry point to annual member research and development activity of $1B, MI provides a gateway for investors and licensees who wish to access Ontario’s technology assets.

During the 2012 BIO convention in Boston, Dr. Hofstein blogged about how CQDM of Montreal and MaRS Innovation of Toronto had teamed up to help “fill” the QC-Ontario corridor and why the corridor is good for business in both provinces.

Encycle TherapeuticsIn my previous blog post during BIO2012, I talked about how MaRS Innovation and CQDM had jointly collaborated to form Encycle Therapeutics, a startup that was created around disruptive technology, developed by Professor Andrei Yudin of the University of Toronto, involving the cyclization of biologically active peptides.

A year later, I’m pleased to report that Encycle is alive and kicking. The company has since recruited seasoned management, and its developing product line is drawing tremendous interest from global pharmaceutical groups. In the next few months, we expect Encycle to raise significant capital and establish meaningful ties with strategic allies.

Taking a wider look at the life sciences sector, this has been a vintage year for Ontario in general and MaRS Innovation’s ecosystem in particular.

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MaRS Innovation on The Agenda’s 3D Printing Epsiode

MI’s Fanny Sie and Shotlst Co-founder Matt Ratto talk bioprinting, healthcare, civil rights and home manufacturing with Steve Paikin

Fanny Sie, project manager in physical sciences and medical devices with specialization in medical imaging, appeared on TVO’s The Agenda on June 5, 2013 to discuss 3D printing.

MaRS Innovation Project Manager Fanny Sie discusses 3D printing, the Bioprinter technology and the implications for society and human health on TVO's The Agenda.
MaRS Innovation Project Manager Fanny Sie discusses 3D printing, the Bioprinter technology and the implications for society and human health on TVO’s The Agenda.

Click here to watch Fanny Sie on The Agenda.

Sie manages the Bioprinter technology, which was touched upon during the interview. The bioprinter was invented by Axel Guenther, a professor in the University of Toronto’s Department of Mechanical and Industrial Engineering, PhD student Lian Leng and a team of other researchers.

The Globe and Mail covered the Bioprinter’s development on January 20, 2013; an excerpt of their interviews with Leng and Guenther was included in the program.

Bioprinting and the Internet of Things

The Agenda’s 3D printing episode also included a second segment exploring its implications for home manufacturing and civil liberties. The guests included Matt Ratto, assistant professor in U of T’s Faculty of Information and co-inventor and CEO of Shotlst (a UTEST company).

Matt Ratto, co-founder of Shotlst and director of the Critical Making Lab, discusses 3D printing, home manufacturing and civil liberties on TVO's The Agenda.

Professor Matt Ratto, co-founder of Shotlst and director of the Critical Making Lab, discusses 3D printing, home manufacturing and civil liberties on TVO’s The Agenda.

Click here to watch Professor Matt Ratto on The Agenda.

Ratto described his experience downloading and printing the Liberator, a gun that can be printed using 3D printing technology, to better understand the process required and the resulting gun’s capabilities.

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MI’s Fanny Sie and Shotlst Founder Matt Ratto to appear on TVO’s The Agenda 8 pm

Fanny Sie, project manager, MaRS Innovation
Fanny Sie, project manager in physical sciences and medical devices , MaRS Innovation.

MaRS Innovation’s Fanny Sie, project manager in physical sciences and medical devices with specialization in medical imaging, is appearing on TVO’s The Agenda with Steve Paikin at 8 pm on June 5, 2013 to discuss 3D printing and the technology’s applications in healthcare and other aspects of human society.

Sie manages the Bioprinter technology, which was invented by Axel Guenther, a professor in the University of Toronto’s Department of Mechanical and Industrial Engineering, PhD student Lian Leng and a team of other researchers. The Globe and Mail covered the Bioprinter’s development on January 20, 2013.

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Five UTEST companies to tackle critical healthcare challenges

Program’s second cohort includes eQOL, E-Twenty Development, Root2Crown, Treata Smart Solutions and TrendMD

University of TorontoTORONTO (May 14, 2013) — Five companies tackling pervasive healthcare challenges — such as assessing dental health, helping patients and medical personnel navigate hospitals with greater ease, staying current with medical literature, or creating digital tools to help care for the elderly or those with chronic health conditions — have been admitted to the University of Toronto Early Stage Technology (UTEST) program’s second cohort.

UTEST, supported by the University of Toronto’s Connaught Fund, Innovations & Partnerships Office (IPO) and MaRS Innovation (MI), is part of a growing system of incubators and commercialization support services at U of T.

Two companies in UTEST’s second cohort, E-Twenty Development Inc. and Treata Smart Solutions Inc. are participating in Canada 3.0 at the Metro Convention Centre May 14 and 15, 2013, in Toronto.

This announcement was covered in PE Hub.

Each company will receive up to $25,000, incubation space in the MaRS Discovery District, mentoring and business strategy support to develop protectable intellectual property, launch their products and gain market traction. They are also eligible to become clients of MaRS Discovery District’s ICE or Healthcare practices.

UTEST seeks scalable, enterprise-focused software applications interested in building business-to-business customer bases — and preferably operational products with a short term to market. The program is co-directed by Kurtis Scissons (U of T IPO) and Dr. Lyssa Neel (MI).

The second cohort has big shoes to fill. UTEST’s first cohort has collectively secured over $1.2 million in follow-on funding and currently employs 29 highly skilled people (HQPs). Each company also filed solid patent protection and most have secured customers. Notably, Whirlscape’s Indiegogo campaign secured over $87,000 in crowd-sourced product funds from nearly 10,000 users, and was featured in the Financial Post, TechCrunch, Mashable and The Verge, among other global media outlets.

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Financial Post profiles OtoSim Inc.’s innovative medical learning device

OtoSim Inc. Logo“If there’s one profession for which you don’t want students to have learning gaps, it’s medicine,” Rebecca Walberg wrote in the Smart Shift: Agenda for Innovation section in the Financial Post on May 7 (reprinted in the Vancouver Sun on May 9 and in the Calgary Herald on June 6, 2013). “Yet that’s exactly what Dr. Paolo Campisi saw while working with medical students at the University of Toronto.”

Walberg’s article, “Innovation in medical learning a Canadian business success story,” describes the process Campisi and his colleague and co-founder Dr. Vito Forte, both of the Hospital for Sick Children and cross-appointed to U of T, undertook to design the OtoSim device, which addresses the gap in how students were learning skills associated with otolaryngology (ear, nose and throat diseases or infections).

Here’s an excerpt (beginning with a quote from Dr. Forte):

“The answer wasn’t more time to lecture or show big pictures on a screen, but rather some kind of instrument that would mimic the experience of looking into an ear with an otoscope. And we went through a number of prototypes developing a simulator that can do just that.”

The result is the OtoSim, brought to market and sold by OtoSim Inc. The simulator consists of a rubber ear made to scale, and a computer display integrated into the model where the eardrum would be in a patient, which can display images of ear canals that correspond to a wide range of medical conditions.

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TechWomen Canada selects UTEST co-director for Silicon Valley program

Lyssa Neel
Lyssa Neel, co-director of UTEST and MaRS Innovation project manager

MaRS Innovation’s (MI) Lyssa Neel, co-director of the UTEST program and project manager, has been selected to represent MI’s ICT start-up companies at the TechWomen Canada program in San Francisco, which runs May 13 to 16, 2013.

The announcement was covered in TechVibes:

TechWomen Canada is run by the Canadian Consulate and is focused on providing Canadian women leaders in the ICT sector an opportunity to expand both professional and business networks in Silicon Valley.

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ClevrU Corp. acquires NewMindsets Inc. to transform online education market

Deal strengthens competitiveness of online learning platform for global mobile learners

The ClevrU platform will integrate New Mindsets Inc.'s technology through this acquisition.
The ClevrU platform (shown here) will integrate NewMindsets Inc.’s technology through this acquisition.

WATERLOO, ON, Canada (April 23, 2013) — ClevrU Corporation today announced that it has acquired NewMindsets Inc., a company founded on online pedagogy researched and developed by two Schulich School of Business professors that has provided leading-edge educational content and services to over 10,000 Schulich students at York University over the past decade.

Through the acquisition, ClevrU will fully integrate NewMindsets’ proven e-teaching pedagogy in leadership, researched and developed by Professors Gareth Morgan and Jean Adams, into its world-class e-teaching platform, to be presented to York as a pilot and then delivered to millions of students worldwide.

TechVibes, EdSurge, Private Equity Hub, Yonge Street Media, and the Waterloo Record covered this announcement. The release is also viewable on CNW and in Chinese (.pdf).

The two companies announced a partnership in October 2012 to establish a second-generation online learning standard.

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