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Call for Applications: MSc Proof-of-Principle Program

Ontario Centres of ExcellenceThe Medical Sciences Proof-of-Principle (MSc PoP) program, administered by Ontario Centres of Excellence on behalf of Ontario’s Ministry of Research & Innovation, is a province-wide initiative for which MaRS Innovation accepts applications from our 15 member institutions.

MaRS Innovation is currently recruiting applications for the July 30, 2015 August 27, 2015 (2 pm) deadline; for submissions to be considered via MI, paperwork must be in byAugust 24, 2015 (4 pm).

We’ve also learned there will be a second call for MScPoP applications in January 2016 after the current round has closed. The third and final call for applications is scheduled for September 2016.  All programs will be run using the same criteria (see below).

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MI’s head of imaging technologies quoted on bioprinting in U.K.’s Financial Times

Fanny Sie
Fanny Sie, head of imaging technologies, is also a manager with MaRS Innovation’s Technology & Venture group.

Fanny Sie, MaRS Innovation’s head of imaging technologies, was quoted in Tanya Powley‘s article, “Printing whole organs remains a long way off,” for the U.K.’s Financial Times on June 11, 2015, regarding the technology’s potential to transform existing healthcare practices.

MI does wish to note that the article inaccurately attributes the PrintAlive device’s development to MaRS Innovation; MI is working with the University of Toronto inventing team, led by Dr. Axel Gunther, to commercialize the device.

Here’s a short excerpt:

Bioprinting could save pharmaceutical companies a lot of money, according to Fanny Sie of MaRS Innovation, a Toronto-based company. The company has developed the PrintAlive Bioprinter, which can print skin that could be used to treat people with large scale burns. The printed tissues could be used by pharmaceutical companies to test the toxicity of new drugs, and help them decide if it is worth starting costly animal and then human clinical trials.

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MaRS Innovation forms third collaboration with Johnson & Johnson Innovation

MaRS Innovation LogoMaRS Innovation today announced that Johnson & Johnson Innovation has expanded its collaboration with MaRS Innovation to identify and advance early-stage technologies of interest.

The announcement was made in advance of the 2015 BIO Convention, which takes place from June 15 to 18 in Philadelphia, PA. MaRS Innovation is participating as part of the Ontario delegation and will have kiosk space in the Ontario pavilion (#615).

This partnership was covered in BioCentury, GEN, PharmaBiz and FierceBiotech.

Earlier this year, Johnson & Johnson Innovation and MaRS Innovation announced their research partnership to advance three technologies focused on improving cardiac surgery outcomes, developing a blood test for depression, and identifying a diagnostic metabolite for both gestational and type 2 diabetes patients. The projects’ principal investigators are researchers from the University Health Network (Peter Munk Cardiac Centre), the Centre for Addiction and Mental Health (with Indoc Research) and the University of Toronto.

“Johnson & Johnson Innovation is an excellent partner that understands exactly the kind of technology pipeline MaRS Innovation represents,” said Dr. Raphael Hofstein, president and CEO. “Renewing their longstanding relationship signals the value they see in this partnership with MaRS Innovation, our members and researchers within our network.”

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Dr. Raphael Hofstein in Biotechnology Focus: It’s time to declare an end to Canada’s two research solitudes

Dr. Raphael Hofstein
Dr. Raphael Hofstein, president & CEO, MaRS Innovation.

Biotechnology Focus, a compendium of the Canadian life sciences industry, has published a guest column by Dr. Raphael Hofstein, MaRS Innovation’s president & CEO, and Elizabeth Monier-Williams, director of marketing and communications.

The article explores the way research focused on discovery and commercialization are often viewed or positioned as competitors within the funding ecosystem and the need to align their goals:

The time of Canada’s French and English solitudes may be past, as Governor General Michaëlle Jean notably stated when she took office in 2005, but the solitudes of thought concerning how Canada supports basic and commercial research persist.

This thinking is most easily spotted after the government announces a federal budget, triggering a flurry of opinion pieces debating the breakdown for the $2.7 billion Canada spends on research.

Most recently, Jim Balsillie, co-founder of Research in Motion (now BlackBerry Ltd.), wrote for the Globe & Mail about the Canadian need to understand that “geopolitics is at the heart of commercializing ideas,” and create better policies to protect Canadian ideas, including “better
incentives for researchers to spur commercialization,” such as during an academic’s consideration for tenure. Yet, like any business endeavor whose success depends on people, there’s more involved in changing Canada’s approach to commercialization than just policy.

The people must want to change, too.

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What Wayne Gretzky taught me about business in 20 minutes

Editor’s note: We don’t usually post personal essays on MI’s website, but we couldn’t pass on this one. Whether you’re a hockey fan or an entrepreneur looking for a fresh business perspective, we hope you’ll agree.

Last Wednesday, I was meeting an old friend for lunch in downtown Toronto. We’re both from Edmonton; we were classmates at the International Space University in Strasbourg, France. And we’re hockey fans. So I said, “Let’s have lunch at Wayne Gretzky’s.”

We didn’t expect to meet Wayne himself, but that’s what happened. One minute I was eating fish tacos. The next minute, my friend’s pointing with his fork: “Dude, Wayne Gretzky’s right behind you.”

Wayne Gretzky (centre) and MI's Hassan Jaferi (right) with X.
Wayne Gretzky (centre) and MI’s Hassan Jaferi (right) with Matthew Killick.

I was in Grade 2 when Gretzky’s Edmonton Oilers won the Stanley Cup in 1987. One of my classmates was the daughter of Andy Moog, the team goalie. He brought the cup into class after the Oilers won so we could all touch it. I grew up playing street hockey in Edmonton and idolizing Wayne. We all did.

So you’ll understand that we had to stop him and say hi. We just had to.

And then we were stunned when he put his glass down on our table and spent 20 minutes talking to us about his various business activities.

My hands were shaking as we left the restaurant an hour later. But here’s five things I managed to take away from this surreal and wonderful experience.

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Funding call: MaRS Innovation Industry Access Program (MI-IAP) accepting applications to February 6

Researchers working in orphan indications, immuno-oncology, respiratory diseases, diabetes, and other key areas invited to submit a brief Statement of Interest

The commercialization process: Moving transformational ideas from the lab bench to the street
MaRS Innovation’s commercialization process helps inventors move their transformational ideas from the lab bench to the street.

The MaRS Innovation Industry Access Program (MI-IAP) is a simple, formalized process for marketing early-stage technologies to MI’s industry partners: Baxter, LifeLabs (formerly CML Healthcare), GSK, Johnson & Johnson, Pfizer and IRICoR/Merck.

The program’s goal is to secure funding for researchers within MI’s membership through these collaborative, strategic R&D partnership programs.

The program is open to any researcher affiliated with MI’s 16 member institutions working on technologies in:

  • Orphan indications
  • Immuno-oncology
  • Respiratory system diseases (e.g., Chronic obstructive pulmonary disease (COPD), asthma, lung cancer, etc.)
  • Diabetes
  • Neuroscience
  • Orthopaedics
  • General surgery

Successfully run in November 2013 and March 2014, the MI-IAP allows researchers to easily determine whether an industry partner is interested in co-developing their technologies. The application process is deliberately brief at the outset.

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BioCentury features Vasomune Therapeutics

Vasomune Therapeutics logoVasomune Therapeutics, a MaRS Innovation start-up company from Sunnybrook Health Sciences Centre’s Sunnybrook Research Institute, was featured in a BioCentury emerging company profile by Michael J. Haas.

The company is currently raising a Series A financing round and recently closed a seed investment with Genome Canada and an unnamed industry partner. MaRS Innovation also contributed a third of the investment, bringing the round’s total to $1.5 million.

Haas’ profile, “Vasomune: Lassoing Tie2,” is available behind a paywall on the BioCentury website.

Here’s a short excerpt:

Agonizing Tie2 could restore vascular integrity and limit tissue damage in kidney injury, but bringing together the four copies needed to activate the receptor is a job too big for small molecules or antibodies. Vasomune Therapeutics Inc. has shown its four-armed peptidomimetic, vasculotide, activates Tie2 and restores vascular integrity in [preclinical]  models.

“Many renal diseases are ultimately characterized by a loss in vascular integrity that damages tubules in the kidney,” CEO Parimal Nathwani said. “Our idea is to use vasculotide to fix the problem and restore normal vascular integrity before it gets out of control.”

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Kaypok, MI’s director of intellectual property quoted in the Financial Post

Article focuses on importance of intellectual property protection for small businesses

StacyIvanchuck8791
Dr. Stacey Ivanchuk, director of intellectual property for MaRS Innovation.

Dr. Stacey Ivanchuk, MaRS Innovation’s director of intellectual property, was quoted in Denise Deveau’s article, “Intellectual property protection is a game small businesses can’t afford to lose,” for the Financial Post on September 26, 2014 regarding the importance of protecting intellectual property for small businesses.

Here’s an excerpt:

Stacey Ivanchuk, director of intellectual property for MaRS Innovation in Toronto, says that protecting a startup’s technology is important especially from an investor’s perspective.

“One of the first questions investors will ask a company is, what is your IP position? To them it’s something they can talk about as an asset and shows that you are distinguishing yourself,” [Dr.] Ivanchuk said.

Ivanchuk said businesses run the gamut from doing nothing to protect their ideas to filing for patents on every idea that comes out of a brainstorming session. “Too early is not good because it can be a waste of money if the proof you expected down the road doesn’t happen,” she said. “But if you wait too long someone might beat you to the punch.”

Kaypok logoThe article also quotes Atul Asthana, CEO of Kaypok, a tech start-up in the text analytics space spun out from York University in partnership with MaRS Innovation:

In the high tech world especially, it’s not always easy to determine whether something should be protected or not, according to Mr. Asthana. “You have to be able to enforce it. If you do it poorly, you will be giving your ideas away and spending a whole bunch of money. It can become a real cat and mouse game sometimes,” he said.

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Tech Transfer Central features MaRS Innovation’s partnership with St. Michael’s Hospital

St. Michael's Hospital LogoTech Transfer Tactics, the monthly newsletter for Tech Transfer Central.com, has published a feature highlighting MaRS Innovation’s Technology Transfer & Scouting (MITTS) services to St. Michael’s Hospital.

The interview explores the increase in disclosures and commercial activity achieved after MaRS Innovation began offering technology transfer services to the hospital, and was triggered by a July profile published on MaRS Innovation’s website describing the collaborative working relationship between the two organizations.

The interview includes conversations with Sahail Shariff, commercialization manager in the MITTS division, and Samar Saneinejad, director of strategic projects in the Office of the Vice President of Research at St. Michael’s, explores the success

Here’s an excerpt:

MaRS Innovation, a member institution of the Networks of Centres of Excellence of Canada, has dramatically increased invention disclosures at St. Michael’s Hospital in Toronto by providing hospital researchers with an embedded technology transfer expert who offers commercialization guidance and access to other vital tech transfer resources.

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MaRS Innovation and St. Michael’s Hospital revitalizing commercialization process

St. Michael's Hospital LogoFor principal investigators, a key component in taking their research ideas from the bench to the market is knowing what commercialization resources exist and when to use them.

Through the MaRS Innovation’s Technology Transfer & Scouting division (MITTS), manager Sahail Shariff is connecting with principal investigators (PIs) at St. Michael’s Hospital in Toronto on the front-line to better understand and advance their research.

Of the 180 PIs at the hospital, the majority are clinician scientists who spend a portion of their time caring for patients.

In collaboration with Samar Saneinejad, project director in the Office of the Vice-President, Research at St. Michael’s, Shariff established a research commercialization committee with regular monthly meetings to stay connected to PIs and their research status. He’s also taken note of the time constraints facing clinician scientists, making a point to provide them with more one-on-one time.

Sahail Shariff
MaRS Innovation’s Sahail Shariff walks the halls at St. Michael’s Hospital to provide better commercialization resources to its researchers.

Invention disclosures from researchers at St. Michael’s have increased by almost 50 percent since October 2013, when Shariff joined MaRS Innovation. He has played a key role in this success and has also helped the hospital to acquire five commercialization-related funding applications and assisted in 12 interactions between PIs and industry members.

“Walking the halls has been really valuable for investigators who have great ideas and have spent a lot of time on their research and inventions, but don’t have excess time to devote to finding the right way to develop it further,” says Shariff.

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