Former Orlando Magic player new innovation director for basketball smartwatch app
This article is republished with the kind permission of Brianna Goldberg and our friends at U of T News.
UTEST company Onyx Motion has partnered with NBA shooting guard Ben Gordon to raise the calibre of digital basketball coaching offered by the company’s first-of-its-kind technology, a smartwatch app that offers on-court skills guidance. The company announced Gordon’s role in helping to further develop the app, called Swish, on July 8 when launching their Indiegogo campaign.
“We’re hoping to build a motion marketplace — a library of data, moves and audio tips from pro players,” said Onyx Motion co-founder and CEO Marissa Wu.
Swish uses smartwatch motion sensors to analyze athlete techniques and offer straightforward tips on how a player can improve.
“The Swish technology is bringing users closer to their favourite basketball player by giving them the opportunity to learn from them,” said Gordon. “I’m excited to work with the team on the further development of this one-of-a-kind experience and help players at any level improve their game.”
TORONTO (July 9, 2015) — Xagenic, a molecular diagnostics company developing the lab-free Xagenic X1™ platform for point-of-care use, today announced that it has raised $15 million (CAD). Each of the company’s Series B investors has participated in this financing, including Domain Associates, CTI Life Sciences, BDC Capital and the Ontario Capital Growth Corporation.
In June, Xagenic also announced it has acquired exclusive rights to a mutation detection technology with potential applications to liquid biopsy testing. The electrochemical clamp assay technology was developed by University of Toronto Professor and Xagenic Founder (now CTO) Dr. Shana Kelley. Genome Web covered the news in June and July 2015.
“This investment round is a testament to the faith our existing investors have in the power of the Xagenic X1™ platform and the promise of our enzyme-free approach to molecular diagnostics,” said Timothy I. Still, Xagenic’s CEO. “This funding will accelerate our development efforts in bringing our point-of-care diagnostic platform to market.”
Xagenic’s rapid, lab-free, molecular diagnostic system affords a large market opportunity created by a significant, unmet medical need for point-of-care diagnostic solutions. Because of its highly scalable, consumables-driven business model, Xagenic is well-positioned to capitalize on this opportunity with a differentiated product offering and unique menu strategy.
XOR Labs Toronto, a Canadian company spun off from the University Health Network in partnership with MaRS Innovation, was profiled by VICE's Motherboard for their technology. They've developed an advanced…
CQDM and MaRS Innovation investing in new Encycle project to determine rules for making peptide drugs orally bioavailable
Encycle Therapeutics is generating a better understanding of the chemical properties required to make small peptide-like molecules, which Encycle calls nacellins, orally bioavailable. With these rules, Encycle will target many of the proteins that are currently regarded as undruggable.
PHILADELPHIA (June 16, 2015) — FiercePharma has predicted that the pharmaceutical industry stands to lose $44 billion in drugs going off patent in 2015. The industry is searching for new therapeutics to replenish their pipelines while tackling existing and new drug receptor targets within the cell, improve patient care and lower administrative costs. In this context, drugs that can be orally swallowed, known as orally-bioavailable drugs, are in great demand.
Encycle Therapeutics Inc., a biotechnology company founded by Dr. Andrei Yudin of the University of Toronto in partnership with MaRS Innovation, is a Canadian start-up emerging as a market leader in finding orally-bioavailable molecules. Today, the company announced $840,000 in funding from CQDM and MaRS Innovation to generate a better understanding of the chemical properties required to make small peptide-like molecules, which Encycle calls nacellins, orally bioavailable.
This funding, generated through MaRS Innovation’s strategic partnerships programs with Pfizer Inc. and GSK, and CQDM’s global membership program with Pfizer Inc. and Merck, brings Encycle’s total funding to approximately $4 million, including an earlier investment in 2011 from Ontario Centres of Excellence.
Dr. Diane Gosselin, president and CEO of CQDM, together with Dr. Raphael (Rafi) Hofstein, president and CEO of MaRS Innovation, made the announcement this morning at the 2015 BIO International Convention in the presence of Dr. Reza Moridi, Ontario Minister of Research and Innovation and Minister of Training, Colleges and Universities, and Dr. Gaétan Barrette, Quebec Minister of Health and Social Services.
“Encycle’s proprietary cyclized peptides are very different from other types of therapeutics and should enable us to target many of the proteins that are currently regarded as undruggable,” says Dr. Jeffrey Coull, Encycle’s president and CEO. “Our research suggests that, due to their unique properties, it’s easier for our peptides to cross cell membranes than it is for other types, allowing them to be taken orally and access proteins on the inside of a cell. Working on this project together with Pfizer and Merck through CQDM, as well as Pfizer and GSK through MaRS Innovation, we now wish to develop a more precise understanding of the relationship between their structure and composition, and the ability to be delivered orally.”
Fanny Sie, head of imaging technologies, is also a manager with MaRS Innovation’s Technology & Venture group.
Fanny Sie, MaRS Innovation’s head of imaging technologies, was quoted in Tanya Powley‘s article, “Printing whole organs remains a long way off,” for the U.K.’s Financial Times on June 11, 2015, regarding the technology’s potential to transform existing healthcare practices.
MI does wish to note that the article inaccurately attributes the PrintAlive device’s development to MaRS Innovation; MI is working with the University of Toronto inventing team, led by Dr. Axel Gunther, to commercialize the device.
Here’s a short excerpt:
Bioprinting could save pharmaceutical companies a lot of money, according to Fanny Sie of MaRS Innovation, a Toronto-based company. The company has developed the PrintAlive Bioprinter, which can print skin that could be used to treat people with large scale burns. The printed tissues could be used by pharmaceutical companies to test the toxicity of new drugs, and help them decide if it is worth starting costly animal and then human clinical trials.
Dr. Raphael Hofstein, president & CEO, MaRS Innovation.
Biotechnology Focus, a compendium of the Canadian life sciences industry, has published a guest column by Dr. Raphael Hofstein, MaRS Innovation’s president & CEO, and Elizabeth Monier-Williams, director of marketing and communications.
The article explores the way research focused on discovery and commercialization are often viewed or positioned as competitors within the funding ecosystem and the need to align their goals:
The time of Canada’s French and English solitudes may be past, as Governor General Michaëlle Jean notably stated when she took office in 2005, but the solitudes of thought concerning how Canada supports basic and commercial research persist.
This thinking is most easily spotted after the government announces a federal budget, triggering a flurry of opinion pieces debating the breakdown for the $2.7 billion Canada spends on research.
Most recently, Jim Balsillie, co-founder of Research in Motion (now BlackBerry Ltd.), wrote for the Globe & Mail about the Canadian need to understand that “geopolitics is at the heart of commercializing ideas,” and create better policies to protect Canadian ideas, including “better
incentives for researchers to spur commercialization,” such as during an academic’s consideration for tenure. Yet, like any business endeavor whose success depends on people, there’s more involved in changing Canada’s approach to commercialization than just policy.
TORONTO (May 27, 2015) – LegWorks Inc., backed with a $2 million blend of private and Government of Canada investments catalyzed by Grand Challenges Canada, is a new Toronto-based company that will contribute to a better life for amputees in developing countries.
The LegWorks AT-knee was covered in the Toronto Star on June 1, 2015 in “Great advances being made in assistive technology” by Kate Allen and in Healio Orthotics & Prosthetics News on June 2.
The LegWorks “All-Terrain Knee” (AT-Knee) is a safe, high-functioning, durable, affordable prosthetic knee joint developed at Toronto’s Holland Bloorview Kids Rehabilitation Hospital. It enables lower-limb amputees to walk more efficiently, safely and comfortably. Its patented design provides incredible stability, is easy to fit and maintain, and can even be used in harsh environments, including water.
“With the AT-Knee and LegWorks, it is our goal to begin to provide more universal access to better prosthetic care for individuals living with amputations around the world,” said Jan Andrysek, scientist in the Bloorview Research Institute at Holland Bloorview Kids Rehabilitation Hospital. “We want to make high-quality and well-functioning prosthetic devices affordable and accessible for the many individuals whose needs are currently left unmet.”
In trials, early users in 10 countries reported a 95 per cent preference for the relatively low-cost AT-Knee to more expensive existing technologies. Developed with a $100,000 Grand Challenges Canada seed grant awarded in 2012 to the Bloorview Research Institute, the AT-Knee easily outperformed existing technologies under rigorous conditions in El Salvador, Chile and Myanmar.
With the new funding, LegWorks will mass produce its innovative, affordable prosthetic knee, the All-Terrain Knee (AT-Knee), the functionality and durability of which makes it ideal for amputees living in the developing world. The $2 million investment deal includes a loan via Grand Challenges Canada of up to $1 million (of which $405,000 has been dispersed), matched by MaRS Innovation, Holland Bloorview Kids Rehabilitation Hospital, Ontario Centres of Excellence and a group of private angel investors. With the $1 million expected from private investors and foundations matched by federal funds, the project will receive an anticipated $2 million to scale-up the success of the company.
In the first five years, LegWorks expects 37,000 units to be sold via distributors, NGOs, prosthetic clinics and government rehab facilities, in both high-income countries and the developing world.
Vodafone expands Toronto-based company’s global partners to advance mobile platform offerings
TORONTO, April 28, 2015 – Vodafone, one of the world’s largest global mobile carriers, has led a second closing of Flybits’ Series A round through Vodafone Ventures. The announcement builds on Flybits’ previously announced Series A financing in August 2014, which was led by Robert Bosch Venture Capital and Trellis Capital.
As an innovative software-as-a-service (SaaS) company, Flybits enables consumer-focused enterprises to expand and manage mobile experiences that deliver targeted content and services. Its platform enhances mobile services to deliver a better customer experience, drive sales and capture analytical insight to establish a competitive advantage. The Flybits solution is easy to deploy, user-friendly and scalable.
“We’ve enjoyed an excellent partnership with Vodafone since beginning an incubation project with them almost two years ago,” said Dr. Hossein Rahnama, founder and chief product officer of Flybits. “They helped us make our product carrier-grade, and this investment will allow us to leverage their presence in more than 21 countries. With the support of our strategic investors, Bosch and Vodafone, our plan is to become the leading platform for companies to develop and deliver intelligent and context-aware mobility solutions.”
“I congratulate Flybits on today’s announcement,” said the Honourable Ed Fast, Minister of International Trade. “Flybits has used many of the services our government offers to help Canadian businesses succeed abroad including the Canadian Technology Accelerators (CTA). Through our network of Trade Commissioners and various programs, this government is committed to helping companies such as Flybits grow beyond our borders to expand globally, creating jobs and economic prosperity across Canada.”
TORONTO, ON (April 23, 2014) — MaRS Innovation congratulates the Federal Government’s deepened commitment to support Canadian research and innovation, particularly in the healthcare sector. In particular, the $42 million over five years dedicated to support the Canadian Centre for Aging and Brain Health Innovation at Baycrest Health Sciences, which includes $32 million in support from the Federal Economic Development Agency for Southern Ontario (FedDev).
Baycrest is a founding member institution of MaRS Innovation.
“As a Baycrest partner and long-time champions of the commercialization potential of its world-class science in brain and geriatric health care, MaRS Innovation welcomes this news,” says Dr. Raphael (Rafi) Hofstein, president and CEO. “We look forward to advancing existing neuroscience projects in partnership with Baycrest, such as The Virtual Brain, and to collaborating on new start-up companies and licenses related to dementia and other neurodegenerative diseases.”
Other promising budget allocations for the innovation sector include:
TORONTO and SAN DIEGO, (April 22, 2015) — Triphase Accelerator Corporation, a private drug development company dedicated to advancing novel compounds through Phase II proof-of-concept, today announced that it has initiated a Phase I proof-of-concept clinical study of marizomib. The study is evaluating an intravenous (IV) formulation of marizomib, a novel and highly potent proteasome inhibitor, in combination with bevacizumab (Avastin®) in patients with glioblastoma, the most common and aggressive malignant primary brain tumor.
The study is recruiting and enrolling patients at the UC Irvine Health Comprehensive Brain Tumor Program at the University of California, Irvine, with Daniela Bota, M.D., Ph.D., and at The Preston Robert Tisch Brain Tumor Center at Duke University Hospital with Annick Desjardin, M.D.
UTEST company Onyx Motion has partnered with NBA shooting guard Ben Gordon to raise the calibre of digital basketball coaching offered by the company’s first-of-its-kind technology, a smartwatch app that offers on-court skills guidance. The company announced Gordon’s role in helping to further develop the app, called Swish, on July 8 when launching their Indiegogo campaign.
Swish uses smartwatch motion sensors to analyze athlete techniques and offer straightforward tips on how a player can improve.
