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Xagenic announces $6 million GAAP partnership for Hepatitis C testing; appoints president and CEO

Xagenic 2014 logoXagenic Inc., a molecular diagnostics company developing the first lab-free molecular diagnostic platform with a 20 minute time-to-result, announced October 15, 2014 that its project in partnership with the University of Toronto was successful in securing funding from Genome Canada under the Genomic Applications Partnership Program (GAPP).

The funding, announced by the Honourable Ed Holder, Minister of State (Science and Technology) and Dr. Pierre Meulien, president and CEO of Genome Canada, is part of 12 selected projects under Genome Canada’s Genomic Applications Partnership Program (GAPP), on October 15 in Wallenstein, Ontario.

The project titled “Development of Low Cost Testing Chip and Device for Hepatitis C Testing” was approved with funding up to a maximum of $5,999,865 over three years. The Ontario Ministry of Research and Innovation is supporting the project with a grant matching the Genome Canada contribution.

“This is a tremendous opportunity for us to leverage the viral assay development and electrochemical detection expertise in the labs of Dr. Shana Kelley and Dr. Edward Sargent at the University of Toronto to significantly advance our own research programs on several fronts,” said Dr. Graham D. Jack, Xagenic’s senior director of Research and Development. “Under this joint program, we anticipate development of a new lower-cost substrate chip, which will significantly bring down the total cost of our in-cartridge AuRA™ detection technology.

Timothy I. Still appointed Xagenic’s president and CEO

On October 16, 2014, Xagenic also announced that Timothy I. Still has been appointed president and CEO, and will serve as a member of Xagenic Inc.’s board of directors.

This announcement was covered in PE Hub.

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Toronto Star features Minuum keyboard’s successful iPhone product launch

Whirlscape founders William Walmsley (left), Severin Smith and Xavier Snelgrove. The company is a graduate of the UTEST program's first cohort.
Whirlscape founders Will Walmsley (left), Severin Smith and Xavier Snelgrove. The company is a graduate of the UTEST program’s first cohort.

UTEST graduate Whirlscape was featured in Raju Mudhar’s Toronto Star article, “Toronto’s Whirlscape debuts tiny Minuum keyboard on iPhone,” which examines the company’s successful launch of their innovative, one-line keyboard for Apple’s iOS 8.

The UTEST program, co-directed by MaRS Innovation and the University of Toronto’s Innovations & Partnerships Office, gives nascent software companies start-up funding, office space, mentoring and business strategy support. Whirlscape was among the program’s first cohort.

The article was published October 6, 2014. Here’s an excerpt:

An Indiegogo success 18 months ago, the company created a tiny keyboard called Minuum for Android devices. Now, iOS and the vast Apple market beckoned. It required new hires, a couple months of round-the-clock development, and a practical rebuilding of their product from scratch so it could be ready to launch with iOS 8. All the work paid off: in the first two weeks of availability, they have sold more than 30,000 apps to the new iPhone audience.

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University of Toronto’s entrepreneurship programs to share over $3 million from province’s Campus-Linked Accelerator Program

UTEST among the four U of T entrepreneurship programs to be funded through Ontario’s CLA program

utestThe University of Toronto will receive $3,056,000 in funding over two years from the Ontario government to increase its training and support for student entrepreneurship.

The funding is part of the Campus-Linked Accelerator Program (CLA), announced today by Reza Moridi, Ontario’s Minister of Research and Innovation, and Minister of Training, Colleges and Universities.

“Fostering the entrepreneurial spirit among students is a key component of Ontario’s Youth Jobs Strategy, through programs that help transfer their ideas and skills to the marketplace while creating rewarding careers,” said Minister Moridi. “By partnering with colleges and universities to support entrepreneurship, we are ensuring our province’s business leaders of tomorrow are getting the support they need to succeed today.”

With this funding, U of T will continue to build on its long track record of success in this area by expanding the entrepreneurship opportunities it offers to students, primarily through its four principal accelerators: The Creative Destruction Lab (Rotman School of Management), The Hatchery (Faculty of Applied Science and Engineering), The Impact Centre (Faculty of Arts & Science), and UTEST (The Innovation and Partnerships Office, produced in partnership with MaRS Innovation).

The CLA program provides critical funding that enhances the support U of T and MaRS Innovation offer to our current UTEST companies,” said Kurtis Scissons, co-director of UTEST. “It also allows UTEST to expand to work with a greater number of student entrepreneurs in computer software, and is a catalyst for other UT CLA’s to combine their entrepreneurship efforts in a synergistic, complimentary way.”

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Xagenic’s Shana Kelley named to Globe and Mail’s Top 12 Canadian Innovators

Xagenic 2014 logoDr. Shana Kelley, co-founder of Xagenic Inc. and a professor of biochemistry at the University of Toronto, has been named to the Globe and Mail’s Top 12 Canadian Innovators list.

The contest solicited nominations from across Canada that were assessed by a panel of judges. According to the Globe, the contest “recognizes talented Canadians who not only have great ideas, but also turn them into reality.”

Here’s an excerpt:

Another innovator who is taking on the traditional way of doing things is Ms. Kelley, a winner in the Health category. Ms. Kelley, a University of Toronto professor and founder of Xagenic, developed a lab-free molecular diagnostic platform that can test for cancer and infectious diseases in the field, with results that are available in 20 minutes.

It’s a product, says Mr. [Dan] Debow, [senior vice-president of emerging technologies at Salesforce] that is in line with a bigger trend that’s happening in health care: the decentralization and democratization of diagnostics.

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BioPrinter engineering team wins Canada Dyson Award

This story appears courtesy of our colleagues at U of T Engineering News.

The printer was developed by (clockwise from top right) University of Toronto students Arianna Mcallister and Lian Leng; former student Boyang Zhang and University of Toronto associate professor Axel Guenther. (Photo courtesy of the James Dyson Foundation)
The printer was developed by (clockwise from top right) University of Toronto students Arianna Mcallister and Lian Leng; former student Boyang Zhang and University of Toronto associate professor Axel Guenther. (Photo courtesy of the James Dyson Foundation)

While some of us are using the new power of 3D printers to make smartphone cases and chocolate figurines, two engineering students from the University of Toronto are using them to print functional human skin.

On September 18, Arianna McAllister and Lian Leng were named the Canadian winners of the 2014 James Dyson Award for their invention, the PrintAlive Bioprinter.

This story was covered by CBC News and BBC News. The BioPrinter team is working with MaRS Innovation to commercialize their technology; read the news archive.

This 3D skin printer won four U of T engineers a $3,500 Canada James Dyson Award and a chance to compete for a $60,000 international prize (photo courtesy of PrintAlive and U of T news).
This 3D skin printer won four U of T engineers a $3,500 Canada James Dyson Award and a chance to compete for a $60,000 international prize (photo courtesy of PrintAlive and U of T news).

The machine – created in collaboration with Professor Axel Guenther, alumnus Boyang Zhang and Dr. Marc Jeschke, head of Sunnybrook Hospital’s Ross Tilley Burn Centre – prints large, continuous layers of tissue that recreate natural skin.

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Minuum launches iOS 8 keyboard, expanding product to Apple users

Whirlscape logoWhirlscape, a graduate of the UTEST program’s first cohort (co-managed by MaRS Innovation and the University of Toronto), has launched their little keyboard for big fingers to Apple users.

The software, released to coincide with Apple’s iOS 8 launch, is part of Whirlscape’s larger efforts to develop typing solutions for wearable devices, including smartwatches, Google Glass and other applications.

The Minuum product launch for iOS was covered in TechCrunch, The Next Web and Mobile Syrup, among other tech blogs, and was mentioned in articles dissecting iOS 8’s overall improvements for Apple users (see Yahoo Tech, Mobile Syrup and Digital Trends).

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Whirlscape releases Minuum version 2.11, teases for iOS 8 launch

Minuum on iOS teaser imageWhirlscape, graduates of the UTEST program, made tech headlines last week by releasing a teaser of Minuum, their one-line, mobile keyboard for wearable devices, running on an iPhone.

The announcement and teaser gif were covered in TechCrunch, SlashGear, MobileSyrup and AndroidGuys, among other tech outlets.

From input, the Minuum blog:

We’ve embraced the design philosophies of iOS to refine Minuum into an elegant typing experience centred around our incredibly powerful autocorrect.

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BioCentury features Encycle Therapeutics

Encycle Therapeutics

Encycle Therapeutics, a MaRS Innovation start-up company from the University of Toronto, was featured in a BioCentury emerging company profile by Michael J. Haas.

The company is currently raising a Series A financing round and employs eight people.

Haas’ profile, “Encycle: Oral Macrocycles,” is available behind a pay wall on the BioCentury website.

Here’s a short excerpt:

Macrocycle therapies can block protein-protein interactions that are undruggable with small molecules; however, oral availability and cell penetration remain key challenges. Encycle Therapeutics Inc.’s chemistry platform generates drug-like macrocycles against validated targets to treat diseases for which oral therapies are needed.

Marketed inhibitors of protein-protein interactions include biologics and other molecules large enough to target the wide, shallow surfaces involved in those interactions, but can only bind extracellular targets. Macrocycles can have sufficient size to block protein-protein interactions yet remain small enough to penetrate cells and block intracellular interactions that biologics and small molecules cannot.

Founded on chemistry from University of Toronto for cyclizing peptides and non-peptidic molecules, Encycle’s macrocycles incorporate three features that are not all found in other companies’ compounds — the absence of sulfur, the presence of intramolecular hydrogen bonding motifs, and an upper limit on size, according to President and CEO Jeffrey Coull.

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CBC’s Lang and O’Leary Exchange features Whirlscape’s Minuum keyboard

Whirlscape logoUTEST graduate Whirlscape, makers of the wearable, one-line Minuum keyboard, were recently featured on CBC’s Lang and O’Leary Exchange.

Minuum has also broken the 100 billion pixels mark in screen space saved for its users. Read about it on input, the Minuum blog.

Founder and CEO Will Walmsley was interviewed by Amanda Lang. The footage was also made available on CBC News, and was included in CBC’s weekly summary of the week’s top business stories. Watch the video.

Here’s an excerpt:

Typing on a smartphone is hard enough – imagine doing it on a smartwatch or other wearable device.

A Toronto startup called Minuum is trying to solve that problem with a tiny virtual keyboard.

It’s a downloadable app costing $3.99 that combines a tiny keyboard with a powerful autocorrect that helps you get the message out, no matter how you punch it.

[. . .]

“What really drives us to work on this technology is the future potential it has. The core concept is a keyboard that is just one line of characters, which means if you can imagine typing on a line anywhere, that can be a keyboard,” he said.

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