BlueDot, a Canadian company that helps decision-makers prepare for and response to infectious disease outbreaks, was profiled in the Toronto Star for their work in tracking the Zika virus. The…
MaRS Innovation enjoyed an exceptional year in 2014. Our team continues to collaborate with researchers within our membership to help bridge the commercialization gap between their world-leading research and creating successful start-up companies or licenses.
Here are our picks for the top 10 news stories from MaRS Innovation’s portfolio.
1. Triphase Accelerator Corporation, in which MaRS Innovation is an investor, started the year with a bang by signing a collaboration and option agreement with Celgene Corporation. In October, Triphase initiated a Phase I clinical study to evaluate marizomib in Glioblastoma (GBM) with Celgene, signed an agreement to provide Celgene with an option to acquire a new bi-specific antibody (licensed by Triphase from PharmAbcine) and closed the year by announcing that Triphase’s proteasome inhibitor, marizomib, demonstrates potent synergistic anti-multiple myeloma activity in combination with pomalidomide.
2. Flybits Inc., spun out of Ryerson University, announced a $3.75 million Series A financing with Robert Bosch Venture Capital to advance its context-aware mobile experience platform. The company was also named a Red Herring Top 100 North America winner.
3. XLV Diagnostics Inc., spun out from Sunnybrook Health Sciences Centre and the Thunder Bay Regional Research Institute, secured a $3 million Series A investment round with Boston-based Bernard M. Gordon Unitrust. XLV’s product will provide mammography image quality equivalent to top-of-the-line mammography machines currently in use, and will do so at a fraction of the cost of current generation systems. The funding will support continued product development and regulatory approval.
Dr. Kamran Khan, founder of BioDiaspora, appeared on CBC’s “The National” on September 23, 2014, as part of a health panel examining the current state of the Ebola outbreak in west Africa.
CBC anchor Peter Mansbridge hosted the discussion.
Watch the clip on CBC’s website.
BioDiaspora, spun off from St. Michael’s Hospital in partnership with MaRS Innovation, developed an easy-to-access, web-based solution that generates and communicates customized, actionable intelligence about global infectious disease threats in real-time.
BioDiaspora, a start-up company based on the research of company founder, Dr. Kamran Khan of St. Michael’s Hospital, has identified two mass gatherings in the Islamic world as key possible spread points for the life-threatening MERS coronavirus, which emerged in the Middle East in early 2012.
BioDiaspora’s disease-tracking platform, which correlates uses global air traffic patterns to predict the international spread of infectious disease (as described in the original media release from St. Michael’s Hospital):
The first is umrah, a pilgrimage that can be performed at any time of year but is considered particularly auspicious during the month of Ramadan, which this year began on July 9 and ends on Aug. 7. The second is the hajj, a five-day pilgrimage required of all physically and financially able Muslims at least once in their life. It takes place Oct. 13 to 18 this year and is expected to draw more than 3 million people.
It also identified the Mumbai-India corridor as particularly vulnerable to MERS based on the predicted exit traffic of travelers leaving the hajj and returning to their home countries following the mass religious event.
Khan’s research findings, published in PLOS Currents: Outbreaks, have attracted media coverage from the Times of India, CanIndia, Toronto Star‘s Foreign Desk blog (Jennifer Yang), Science Daily.com, DowntoEarth.org and Homeland Security News Wire.
Dr. Kamran Khan, founder of BioDiapsora, was cited in a New York Times‘ Bits article on the Big Data solutions evolving to track the global spread of disease: “In New Tools to Combat Epidemics, the Key is Context.”
Amy O’Leary‘s article appeared as part of a special blog/supplement on June 19, 2013 (Big Data 2013).
Here’s an excerpt (links and emphasis ours):
One of the doctors in the field who can benefit from these types of insights is Dr. Kamran Khan, an infectious disease specialist and researcher at St. Michael’s Hospital in Toronto.
Dr. Khan, who said he had a “bad habit of being around emerging diseases,” has worked on the front lines of the 1999 West Nile virus outbreak and the H1N1 pandemic of 2009. But the event that hit closest to home was when his own hospital was affected by a deadly outbreak of severe acute respiratory syndrome, or SARS, which hit Toronto in 2003.
Dr. Kamran Khan, founder of BioDiaspora and an infectious disease physician and scientist at St. Michael’s Hospital, is among the experts studying the emergence of the H7N9 bird flu outbreak in China and the new coronavirus in the Middle East and Europe.
Global News National also covered this story on April 11, 2013. Watch Beatrice Politi and Carmen Chai‘s report, “Canadian scientists pioneer new formula in airport disease screening,” on the Global website.
The Toronto Star featured Khan’s research and BioDiaspora following the publication of his new paper in the Bulletin of the World Health Organization which assessed the impact of airport screenings in containing the 2009 H1N1 outbreak in Mexico.
Khan’s findings were covered in “Airport disease screening rarely worthwhile, Toronto study says,” by Helen Branswell.
Dr. Kamran Khan, founder of BioDiaspora and an infectious disease physician and scientist at St. Michael’s Hospital, is among the experts studying the emergence of the H7N9 bird flu outbreak in China.
Jennifer Yang interviewed Khan in today’s Toronto Star about the likelihood of the disease being easily transmitted from human to human or arriving in Canada, as SARS did in 2003.
Here’s an excerpt:
“This isn’t necessarily an event that poses a significant risk to Canada, at least based on all the current knowledge,” said Dr. Kamran Khan, an infectious disease specialist at St. Michael’s Hospital and founder of BioDiaspora, a program that predicts the potential spread of outbreaks. “Even if a case were to find its way into Canada, the likelihood of it spreading locally is quite low.”
BioDiaspora collects data on everything from air travel and weather to global distribution of disease-carrying insects and uses this data to forecast the potential spread of new diseases.
It has already performed a risk analysis of H7N9 for the U.S. Centers for Disease Control and Prevention, which contacted Khan last Tuesday for help.
Health risk to Canadians is currently low
Dr. Kamran Khan, founder of BioDiaspora and an infectious disease physician and scientist at St. Michael’s Hospital, is among the experts studying the emergence of the coronavirus.
Carolyn Brown interviewed Khan for a recent CMAJ article on the viral outbreak, “New coronavirus with ‘pandemic potential’ sparks global surveillance efforts.”
India’s Kumbh Mela, an annual mass Hindu pilgrimage of faith, is unlikely to create a disease outbreak that spreads beyond the country’s borders, Dr. Kamran Khan, founder of BioDiaspora, tells Maclean’s Magazine‘s Hannah Hoag in “As millions gather for Kumbh Mela, doctors are watching” (February 11, 2013).
Here’s an excerpt (emphasis ours):
Unlike the hajj or the Olympics, the Kumbh Mela is primarily a domestic event. While flights into Saudi Arabia spike to five times normal during the hajj, “with the Kumbh Mela, it’s marginal,” says Khan, “probably five to 10 per cent at some airports.”
To help stem disease outbreaks that do cross borders, such as the 2003 SARS outbreak in Toronto, Khan developed Bio.Diaspora, an online tool that shows how international travellers can spread infectious diseases. Khan is also working with another group of scientists—along with the U.S. Centers for Disease Control and Prevention (CDC)—to develop a tool called BioMosaic that maps census data, migration patterns and health status to identify countries where international travel may give rise to emerging disease.
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