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Dr. Raphael Hofstein in Biotechnology Focus: It’s time to declare an end to Canada’s two research solitudes

Dr. Raphael Hofstein
Dr. Raphael Hofstein, president & CEO, MaRS Innovation.

Biotechnology Focus, a compendium of the Canadian life sciences industry, has published a guest column by Dr. Raphael Hofstein, MaRS Innovation’s president & CEO, and Elizabeth Monier-Williams, director of marketing and communications.

The article explores the way research focused on discovery and commercialization are often viewed or positioned as competitors within the funding ecosystem and the need to align their goals:

The time of Canada’s French and English solitudes may be past, as Governor General Michaëlle Jean notably stated when she took office in 2005, but the solitudes of thought concerning how Canada supports basic and commercial research persist.

This thinking is most easily spotted after the government announces a federal budget, triggering a flurry of opinion pieces debating the breakdown for the $2.7 billion Canada spends on research.

Most recently, Jim Balsillie, co-founder of Research in Motion (now BlackBerry Ltd.), wrote for the Globe & Mail about the Canadian need to understand that “geopolitics is at the heart of commercializing ideas,” and create better policies to protect Canadian ideas, including “better
incentives for researchers to spur commercialization,” such as during an academic’s consideration for tenure. Yet, like any business endeavor whose success depends on people, there’s more involved in changing Canada’s approach to commercialization than just policy.

The people must want to change, too.

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Dr. Rafi Hofstein in Biotechnology Focus: What will it take to regain Canada’s biotechnology leadership?

Dr. Raphael Hofstein
Dr. Raphael Hofstein, president & CEO, MaRS Innovation.

Biotechnology Focus, a compendium of the Canadian life sciences industry, has published a guest column by MaRS Innovation President & CEO, Dr. Raphael Hofstein.

The article explores the role life sciences assets, financing and talented management–the three Ms–must play in revitalizing Canada’s biotechnology sector:

At the close of the 20th century, Canada was perceived as a key contributor to the success of the global biotech voyage.

You know what happened next: the mechanisms to fund early ventures collapsed together with the collapse of the Canadian venture capital industry Finding suitable investment for early-stage technologies became incredibly challenging. Facing a dearth of opportunity, talented management sailed for other harbors.

It’s satisfying that on the eve of the 2014 BIO Convention, some indicators suggest to me that we are witnessing a rebound. But to accelerate our pace while holding this bearing, Canada needs to address certain strategic elements.

At MaRS Innovation, we call them the three Ms: merchandize, management and money.

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UTEST’s co-directors share what makes for a great start-up application

utestThe University of Toronto Early-Stage Technology (UTEST) program helps U of T students, recent grads or professors to take their ideas to market.

Successful applicants get mentoring, funding and work space over a 12-month period as they advance their ideas. The program is co-managed by MaRS Innovation and the University of Toronto.

In a U of T “Spotlight on Startups” news article, Brianna Goldberg spoke with Mike Betts and Kurtis Scissons, UTEST co-directors, on what makes for a great applicant.

Here’s an excerpt:

What are you looking for in an exceptional UTEST application?
Evidence of a strong and committed team.  It’s critical to have standout technology and a great market opportunity but at the end of the day it’s the team that makes these businesses work—it’s about having a balance of amazing technical talent and business leadership and execution skills. When we come across an application that has a really awesome team, it stands out. – Mike Betts, UTEST co-director

What’s one common mistake you see in applications for UTEST that might cause them to be rejected?
Commitment. We want entrepreneurs that are fully committed to the program and to their new companies. UTEST is a serious program for serious entrepreneurs who want support to create a sustainable successful company. The application must exude your confidence in your idea and the effort the entrepreneur(s) will commit to see it successful.  Kurtis Scissons, UTEST co-director

What advice would you give to those considering applying to UTEST?
1. Build a balanced team. Understand the strengths of your team members and ensure that gaps can be addressed either through internal change or be open to external hires.

2. Be passionate about your idea but also understand it will be a rollercoaster of emotions. –Scissons

Betts and Scissons are accepting applications for UTEST’s third cohort until April 17. Current students, current faculty and recent graduates of U of T are welcome to apply.

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Techvibes highlights UTEST’s third cohort

utestTechvibes, a publication dedicated to covering latest trends in start-up culture and social and mobile news, covered the University of Toronto Early-Stage Technology (UTEST) program’s call for applications in an online article on March 1, 2014.

Applications for UTEST’s third cohort are open until April 17, 2014. Co-directors Kurtis Scissons and Mike Betts will work with selected applicants for a period of twelve months to guide their idea to market. Successful applicants receive work space for a year, mentorship, $30,000 in funding and access to industry expertise.

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Whirlscape’s Minuum keyboard makes SmartTV typing easy

University of Toronto Early-Stage Technology (UTEST) graduate Whirlscape Inc. released a video on February 25, 2014 showing how their Minuum keyboard can make typing on Smart TVs and consoles easy.

UTEST is currently accepting applications for its third cohort. Apply now.

Minuum, the “little keyboard for big fingers” is making waves in wearable technology with their disambiguation algorithm and advanced language modelling, which can be used on Android devices and smart watches.

Read Darrell Etherington‘s article about Minuum on Smart TVs and consoles in Tech Crunch and coverage in Geeky Gadgets, an online technology review and resource publication. You can also read more about the U of T science behind Minuum here.

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Xagenic founder Shana Kelley’s MRI blog post on bringing research to market

U of T professor shares tips to her team’s commercialization success

Xagenic logo CroppedWhen it comes to bringing research from the lab to the market, the University of Toronto’s Dr. Shana Kelley knows firsthand what it takes. She’s co-founder of Xagenic, a MaRS Innovation and U of T start-up company that’s developed the first lab-free molecular diagnostic platform with a 20-minute time-to-result based on her research with fellow U of T colleague Professor Edward Sargent.

Xagenic recently announced a Series B financing announcement following their successful $10 million Series A round and more than $2 million seed funding round.

In her guest blog post for the Ministry of Research and Innovation, Kelley outlines what she’s learned through her experience in the commercialization process (emphasis ours):

1. When ready to commercialize, look in your own backyard for investment and support

Shana Kelley, co-founder of Xagenic Inc.
Dr. Shana Kelley, co-founder of Xagenic Inc. and University of Toronto professor.

When the Xagenic technology was mature enough to consider commercialization, we started to call venture investors all over the world to see if we could get them to back the company.  We always got the meetings we wanted, and lots of enthusiasm and encouragement, but it was difficult to get people engaged. We were fortunate to get seed funding from a group of local organizations including MaRS Innovation, Ontario Institute for Cancer Research, the Innovation Acceleration Fund (IAF), and Ontario Centres of Excellence and then finally found the group that would eventually be our Series A lead investors, CTI Life Sciences Fund.

With CTI, we immediately got the traction we had been looking for from a venture investor that indicated genuine interest in the company. When we later made the rounds for the Series B investment outside of Canada, we repeatedly heard the comment: “we’re glad to see you could do the Series A in your own backyard.”

When I probed about why this was important, I found that the investment community thinks it is important to have your early investors as close geographically as possible. The level of interaction when a company gets off the group needs to be fairly intense — being geographically closer helps entrepreneurs and investors keep in better contact. This is definitely not a hard-and-fast rule, but I found it interesting that many investors had this perception. And it creates a particular challenge for Canadian companies given how little venture capital is available locally!

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