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Triphase announces Celgene collaborations and license deal with PharmAbcine

Triphase-logo-WebTriphase Accelerator Corporation, a private, drug development company dedicated to advancing novel compounds through Phase II proof-of-concept, announced October 27, 2014 new and expanded strategic collaborations with Celgene Corporation.

This announcement was covered in Genetic Engineering and Biotechnology News (GEN), BioCentury Extra (no link available), Pharmaceutical Business Review (no link available), Scrip and BioWorld Today (no link available). It builds on Triphase’s original collaborative agreement with Celgene in January 2014.

The company has also announced a new global license for a fully human, bi-specific antibody targeting VEGFR-2/TIE 2 with Korea’s PharmAbcine.

Triphase initiates Phase I Study Evaluating Marizomib in Glioblastoma (GBM) with Celgene

Triphase has expanded its strategic collaboration with Celgene Corporation. The supplemental agreement adds a Phase I development program that will explore combining an intravenous (IV) formulation of marizomib with bevacizumab in glioblastoma (GBM), an aggressive malignant primary brain tumour.

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MI’s Rafi Hofstein featured in Biotechnology Focus

Dr. Raphael Hofstein (left), the Honourable Minister Reza Moridi (centre) and Dr. Mark
MI’s Dr. Raphael Hofstein (left), the Honourable Minister Reza Moridi (centre) and Dr. Mark Poznansky of the Ontario Genome Institute on the January 2014 cover of Biotechnology Focus.

In a January 24, 2014 Biotechnology Focus cover article, author Shawn Lawrence discusses MaRS Innovation President and CEO Dr. Raphael (Rafi) Hofstein‘s recent visit to learn more of the emerging science and technology markets in Singapore and Japan.

The trip allowed Hofstein to discuss current MI projects, specifically start-ups XLV Diagnostics Inc. and DVLR Therapeutics Inc., whose products could benefit from Singapore’s proximity to medical technology markets in India and China.

Hofstein joined other delegates from Canada, including Dr. Mark Poznansky, president and CEO of the Ontario Genome Institute (OGI).

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Is screening air travellers effective in containing a pandemic?

Toronto Star covers Khan’s new WHO paper on H1N1 outbreak

Dr. Kamran Khan, founder of BioDiaspora and an infectious disease physician and scientist at St. Michael’s Hospital, is among the experts studying the emergence of the H7N9 bird flu outbreak in China and the new coronavirus in the Middle East and Europe.

Global News National also covered this story on April 11, 2013. Watch Beatrice Politi and Carmen Chai‘s report, “Canadian scientists pioneer new formula in airport disease screening,” on the Global website.

The Toronto Star featured Khan’s research and BioDiaspora following the publication of his new paper in the Bulletin of the World Health Organization which assessed the impact of airport screenings in containing the 2009 H1N1 outbreak in Mexico.

Khan’s findings were covered in “Airport disease screening rarely worthwhile, Toronto study says,” by Helen Branswell.

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BioDiaspora Founder: Travellers unlikely to bring H7N9 bird flu to Canada

Dr. Kamran Khan, founder of BioDiaspora and an infectious disease physician and scientist at St. Michael’s Hospital, is among the experts studying the emergence of the H7N9 bird flu outbreak in China.

Jennifer Yang interviewed Khan in today’s Toronto Star about the likelihood of the disease being easily transmitted from human to human or arriving in Canada, as SARS did in 2003.

Here’s an excerpt:

“This isn’t necessarily an event that poses a significant risk to Canada, at least based on all the current knowledge,” said Dr. Kamran Khan, an infectious disease specialist at St. Michael’s Hospital and founder of BioDiaspora, a program that predicts the potential spread of outbreaks. “Even if a case were to find its way into Canada, the likelihood of it spreading locally is quite low.”

BioDiaspora collects data on everything from air travel and weather to global distribution of disease-carrying insects and uses this data to forecast the potential spread of new diseases.

It has already performed a risk analysis of H7N9 for the U.S. Centers for Disease Control and Prevention, which contacted Khan last Tuesday for help.

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ClevrU partners with Schulich School of Business professors to target online education market

MaRS Innovation and York University’s commercialization office support new partnership

Students in China interact with the ClevrU platform
Students in China interact with the ClevrU platform. Photo courtesy of ClevrU Inc.

In the age of ITunes, videotaping lectures or converting existing textbooks into e-books won’t make you the market leader in online education.

Thanks to a new partnership between ClevrU, and NewMindsets Inc., facilitated by MaRS Innovation and York University’s commercialization office, Canadian technology and content promises to establish the second-generation online learning standard for millions of students worldwide.

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Business Without Borders highlights ScarX Therapeutics’ Chinese co-development partnership

ScarX logoScarX Therapeutics, a spin-off company created by MaRS Innovation and The Hospital for Sick Children (SickKids), was profiled by Business Without Borders on September 25, 2012.

Sean Fine‘s article examines the strategic funding partnership MI pursued with NovoTek Therapeutics Inc. (NovoTek) in China to develop the anti-scarring cream, which was discovered by researchers at SickKids.

A multibillion-dollar market may await ScarX, a Toronto biomedical start-up, but first it had to figure out how to finance the development of its unique cream that reduces scarring after surgery.

Its answer to the shortage of Canadian venture capital in life sciences turned out to be a partnership with a drug company in China.

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MaRS Innovation Forms Strategic Drug-Development Partnership with NovoTek Therapeutics Inc. in China

ScarX logoMaRS Innovation (MI), The Hospital for Sick Children (SickKids) and NovoTek Therapeutics Inc. (NovoTek)  have announced a strategic partnership to co‐develop, and bring to the Chinese market, a novel therapeutic cream aimed at reducing scar formation post surgery.

This project was covered in The Globe and Mail on May 7, 2012.

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