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Onyx Motion signs NBA’s Ben Gordon and launches Indiegogo crowdfunding campaign

Former Orlando Magic player new innovation director for basketball smartwatch app

This article is republished with the kind permission of Brianna Goldberg and our friends at U of T News.

Onyx-Motion-Swish-app-basketball-coach-1024x675UTEST company Onyx Motion has partnered with NBA shooting guard Ben Gordon to raise the calibre of digital basketball coaching offered by the company’s first-of-its-kind technology, a smartwatch app that offers on-court skills guidance. The company announced Gordon’s role in helping to further develop the app, called Swish, on July 8 when launching their Indiegogo campaign.

“We’re hoping to build a motion marketplace — a library of data, moves and audio tips from pro players,” said Onyx Motion co-founder and CEO Marissa Wu.

Onyx Motion’s Indiegogo crowdfunding campaign launch was covered by: TechVibes, Silicon Angle, IT Business.ca, Canadian Reviewer, Network World, GizMag and Sport Techie.

Swish uses smartwatch motion sensors to analyze athlete techniques and offer straightforward tips on how a player can improve.

“The Swish technology is bringing users closer to their favourite basketball player by giving them the opportunity to learn from them,” said Gordon. “I’m excited to work with the team on the further development of this one-of-a-kind experience and help players at any level improve their game.”

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Xagenic announces $15 million financing round with Series B investors

MI_xagenicTORONTO (July 9, 2015) — Xagenic, a molecular diagnostics company developing the lab-free Xagenic X1™ platform for point-of-care use, today announced that it has raised $15 million (CAD). Each of the company’s Series B investors has participated in this financing, including Domain Associates, CTI Life Sciences, BDC Capital and the Ontario Capital Growth Corporation.

PE Hub, Cantech Letter, Genome Web, Fierce Medical Devices and the Wall Street Journal‘s Venture Capital Dispatch blog covered this announcement.

In June, Xagenic also announced it has acquired exclusive rights to a mutation detection technology with potential applications to liquid biopsy testing. The electrochemical clamp assay technology was developed by University of Toronto Professor and Xagenic Founder (now CTO) Dr. Shana Kelley. Genome Web covered the news in June and July 2015.

“This investment round is a testament to the faith our existing investors have in the power of the Xagenic X1™ platform and the promise of our enzyme-free approach to molecular diagnostics,” said Timothy I. Still, Xagenic’s CEO. “This funding will accelerate our development efforts in bringing our point-of-care diagnostic platform to market.”

Xagenic’s rapid, lab-free, molecular diagnostic system affords a large market opportunity created by a significant, unmet medical need for point-of-care diagnostic solutions. Because of its highly scalable, consumables-driven business model, Xagenic is well-positioned to capitalize on this opportunity with a differentiated product offering and unique menu strategy.

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Call for Applications: MSc Proof-of-Principle Program

Ontario Centres of ExcellenceThe Medical Sciences Proof-of-Principle (MSc PoP) program, administered by Ontario Centres of Excellence on behalf of Ontario’s Ministry of Research & Innovation, is a province-wide initiative for which MaRS Innovation accepts applications from our 15 member institutions.

MaRS Innovation is currently recruiting applications for the July 30, 2015 August 27, 2015 (2 pm) deadline; for submissions to be considered via MI, paperwork must be in byAugust 24, 2015 (4 pm).

We’ve also learned there will be a second call for MScPoP applications in January 2016 after the current round has closed. The third and final call for applications is scheduled for September 2016.  All programs will be run using the same criteria (see below).

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Encycle Therapeutics working with major pharmaceutical companies to design rules for drugs meant to be swallowed

CQDM and MaRS Innovation investing in new Encycle project to determine rules for making peptide drugs orally bioavailable

CQDM announcement
Encycle Therapeutics is generating a better understanding of the chemical properties required to make small peptide-like molecules, which Encycle calls nacellins, orally bioavailable. With these rules, Encycle will target many of the proteins that are currently regarded as undruggable.

PHILADELPHIA (June 16, 2015) — FiercePharma has predicted that the pharmaceutical industry stands to lose $44 billion in drugs going off patent in 2015. The industry is searching for new therapeutics to replenish their pipelines while tackling existing and new drug receptor targets within the cell, improve patient care and lower administrative costs. In this context, drugs that can be orally swallowed, known as orally-bioavailable drugs, are in great demand.

Encycle Therapeutics Inc., a biotechnology company founded by Dr. Andrei Yudin of the University of Toronto in partnership with MaRS Innovation, is a Canadian start-up emerging as a market leader in finding orally-bioavailable molecules. Today, the company announced $840,000 in funding from CQDM and MaRS Innovation to generate a better understanding of the chemical properties required to make small peptide-like molecules, which Encycle calls nacellins, orally bioavailable.

This release was covered in Biotechnology Focus and BioSpace.

This funding, generated through MaRS Innovation’s strategic partnerships programs with Pfizer Inc. and GSK, and CQDM’s global membership program with Pfizer Inc. and Merck, brings Encycle’s total funding to approximately $4 million, including an earlier investment in 2011 from Ontario Centres of Excellence.

Dr. Diane Gosselin, president and CEO of CQDM, together with Dr. Raphael (Rafi) Hofstein, president and CEO of MaRS Innovation, made the announcement this morning at the 2015 BIO International Convention in the presence of Dr. Reza Moridi, Ontario Minister of Research and Innovation and Minister of Training, Colleges and Universities, and Dr. Gaétan Barrette, Quebec Minister of Health and Social Services.

MI_encycle“Encycle’s proprietary cyclized peptides are very different from other types of therapeutics and should enable us to target many of the proteins that are currently regarded as undruggable,” says Dr. Jeffrey Coull, Encycle’s president and CEO. “Our research suggests that, due to their unique properties, it’s easier for our peptides to cross cell membranes than it is for other types, allowing them to be taken orally and access proteins on the inside of a cell. Working on this project together with Pfizer and Merck through CQDM, as well as Pfizer and GSK through MaRS Innovation, we now wish to develop a more precise understanding of the relationship between their structure and composition, and the ability to be delivered orally.”

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Ontario Government Invests $1 Million in Toronto’s Neuroscience Catalyst Consortium

Ministry of Research & Innovation joins founding partners University of Toronto and Janssen Inc., and new partners Evotec AG, MaRS Innovation and Ontario Centres of Excellence, to advance treatments for neurological disorders and develop early-stage biotech companies

From left to right: Dr. Rafi Hofstein, president and CEO of MaRS Innovation; Professor Ruth Ross, director of the Centre for Collaborative Drug Research at the University of Toronto; Guy Seabrook, vice president of Neuroscience Scientific Innovation at Johnson & Johnson Innovation, California; the Honourable Reza Moridi, Minister of Research &Innovation; and Chris Halyk, president of Janssen Inc.
From left to right: Dr. Rafi Hofstein, president and CEO of MaRS Innovation; Professor Ruth Ross, director of the Centre for Collaborative Drug Research at the University of Toronto; Guy Seabrook, vice president of Neuroscience Scientific Innovation at Johnson & Johnson Innovation, California; the Honourable Reza Moridi, Minister of Research &Innovation; and Chris Halyk, president of Janssen Inc.

TORONTO and PHILADELPHIA (June 16, 2015)— Toronto’s neuroscience efforts to find new drugs to treat and manage brain disorders — specifically, mood disorders and Alzheimer’s disease — took another step forward as the Government of Ontario’s Ministry of Research and Innovation announced a $1 million contribution to the Neuroscience Catalyst consortium, bringing the total raised for the open innovation fund to $3.7 million. Reza Moridi, Minister of Research and Innovation and Minister of Training Colleges and Universities, announced the contribution at the 2015 BIO International conference in Philadelphia during the opening of the Ontario pavilion.

This release was covered by Pharma TV and in TechVibes, BioSpace and Biotechnology Focus, and was referenced on the Canadian Science Policy Centre‘s and the Alzheimer Society of Toronto’s respective websites.

“We are pleased to support this collaborative innovation model which will accelerate the development of better treatment options for people with neurological disorders,” said Minister Moridi. “Partnerships between universities, academic hospitals, research institutes, industries and government are key to positioning Ontario as a global leader in Life Sciences.”

Founded by the University of Toronto (U of T) in partnership with Janssen Inc. and facilitated by Johnson & Johnson Innovation, the Neuroscience Catalyst consortium is using the Toronto research community’s well-established strengths in neuroscience to identify promising early-stage molecules and technologies through an open innovation model. The consortium aims to combine expertise to enable and accelerate the translation of basic sciences through to start-up companies and investor partnerships.

“We all want the next generation of solutions that are so desperately needed by patients and their families,” said Professor Ruth Ross, director of the Centre for Collaborative Drug Research at U of T. “In Canada, mood disorders such as depressive disorder and bipolar disorder affect about 10 per cent of the population. Alzheimer’s disease affects more than 745,000 Canadians. The need is urgent and this unique open collaborative partnership will allow us to rapidly develop new treatments.”

Other partners joining the project include MaRS Innovation, which introduced the partners to the Ministry of Research & Innovation and led the early conversation; Evotec, a global, high-quality provider in the drug discovery field; and Ontario Centres of Excellence (OCE), which is administering the funding.

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LegWorks developing better, more affordable prosthetic knees for developing world

TORONTO (May 27, 2015)  – LegWorks Inc., backed with a $2 million blend of private and Government of Canada investments catalyzed by Grand Challenges Canada, is a new Toronto-based company that will contribute to a better life for amputees in developing countries.

The LegWorks AT-knee was covered in the Toronto Star on June 1, 2015 in “Great advances being made in assistive technology” by Kate Allen and in Healio Orthotics & Prosthetics News on June 2.

LegWorks3
Stripping the ability to walk, lower-limb amputation restricts independence, employment potential and productive participation in the community and affects over 10 million people. The WHO estimates that only five to 15 per cent of all lower-limb amputees in the developing world have access to appropriate prosthetic services and technologies — a large unmet need. Photo credit: Patrick Brown © 2014 Panos.

The LegWorks “All-Terrain Knee” (AT-Knee) is a safe, high-functioning, durable, affordable prosthetic knee joint developed at Toronto’s Holland Bloorview Kids Rehabilitation Hospital.  It enables lower-limb amputees to walk more efficiently, safely and comfortably.  Its patented design provides incredible stability, is easy to fit and maintain, and can even be used in harsh environments, including water.

“With the AT-Knee and LegWorks, it is our goal to begin to provide more universal access to better prosthetic care for individuals living with amputations around the world,” said Jan Andrysek, scientist in the Bloorview Research Institute at Holland Bloorview Kids Rehabilitation Hospital. “We want to make high-quality and well-functioning prosthetic devices affordable and accessible for the many individuals whose needs are currently left unmet.”

In trials, early users in 10 countries reported a 95 per cent preference for the relatively low-cost AT-Knee to more expensive existing technologies. Developed with a $100,000 Grand Challenges Canada seed grant awarded in 2012 to the Bloorview Research Institute, the AT-Knee easily outperformed existing technologies under rigorous conditions in El Salvador, Chile and Myanmar.

LegWorks LogoWith the new funding, LegWorks will mass produce its innovative, affordable prosthetic knee, the All-Terrain Knee (AT-Knee), the functionality and durability of which makes it ideal for amputees living in the developing world. The $2 million investment deal includes a loan via Grand Challenges Canada of up to $1 million (of which $405,000 has been dispersed), matched by MaRS Innovation, Holland Bloorview Kids Rehabilitation Hospital, Ontario Centres of Excellence and a group of private angel investors. With the $1 million expected from private investors and foundations matched by federal funds, the project will receive an anticipated $2 million to scale-up the success of the company.

In the first five years, LegWorks expects 37,000 units to be sold via distributors, NGOs, prosthetic clinics and government rehab facilities, in both high-income countries and the developing world.

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Flybits announces second closing of $4.75M Series A financing

Vodafone expands Toronto-based company’s global partners to advance mobile platform offerings

Flybits Corporate LogoTORONTO, April 28, 2015 – Vodafone, one of the world’s largest global mobile carriers, has led a second closing of Flybits’ Series A round through Vodafone Ventures. The announcement builds on Flybits’ previously announced Series A financing in August 2014, which was led by Robert Bosch Venture Capital and Trellis Capital.

This announcement was covered in the Financial Post, TechVibes, PE HUB and BetaKit.

As an innovative software-as-a-service (SaaS) company, Flybits enables consumer-focused enterprises to expand and manage mobile experiences that deliver targeted content and services. Its platform enhances mobile services to deliver a better customer experience, drive sales and capture analytical insight to establish a competitive advantage. The Flybits solution is easy to deploy, user-friendly and scalable.

“We’ve enjoyed an excellent partnership with Vodafone since beginning an incubation project with them almost two years ago,” said Dr. Hossein Rahnama, founder and chief product officer of Flybits. “They helped us make our product carrier-grade, and this investment will allow us to leverage their presence in more than 21 countries. With the support of our strategic investors, Bosch and Vodafone, our plan is to become the leading platform for companies to develop and deliver intelligent and context-aware mobility solutions.”

“I congratulate Flybits on today’s announcement,” said the Honourable Ed Fast, Minister of International Trade. “Flybits has used many of the services our government offers to help Canadian businesses succeed abroad including the Canadian Technology Accelerators (CTA). Through our network of Trade Commissioners and various programs, this government is committed to helping companies such as Flybits grow beyond our borders to expand globally, creating jobs and economic prosperity across Canada.”

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MaRS Innovation statement on the 2015 Federal Budget

mi_logo_squareTORONTO, ON (April 23, 2014) — MaRS Innovation congratulates the Federal Government’s deepened commitment to support Canadian research and innovation, particularly in the healthcare sector. In particular, the $42 million over five years dedicated to support the Canadian Centre for Aging and Brain Health Innovation at Baycrest Health Sciences, which includes $32 million in support from the Federal Economic Development Agency for Southern Ontario (FedDev).

Baycrest is a founding member institution of MaRS Innovation.

“As a Baycrest partner and long-time champions of the commercialization potential of its world-class science in brain and geriatric health care, MaRS Innovation welcomes this news,” says Dr. Raphael (Rafi) Hofstein, president and CEO. “We look forward to advancing existing neuroscience projects in partnership with Baycrest, such as The Virtual Brain, and to collaborating on new start-up companies and licenses related to dementia and other neurodegenerative diseases.”

Other promising budget allocations for the innovation sector include:

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Life Sciences Ontario’s statement on the 2015 Ontario Budget

LSO Building Blocks

TORONTO, ON (April 23, 2015) — Life Sciences Ontario (LSO) applauds the government’s continued commitment to supporting life sciences through the Ontario Health Innovation Council and its accompanying $20 million innovation fund, programs to support job creation for Ontario’s highly educated young workforce and a new approach to providing the venture capital needed to support the commercialization of technologies and growth of companies in the life sciences sector.

Specifically, LSO notes the following commitments from the 2015 budget that will help drive innovation in Ontario:

  • Endorsing the Ontario Health Innovation Council report, which will establish a $20 million Health Technology Innovation Fund and appoint a chief innovation strategist to act on the report’s recommendations.
  • Funding the TalentEdge Program, which provides internships for graduate and postgraduate students and is integral to boosting campus-linked industrial research while developing and commercializing the innovative ideas of young researchers.
  • Committing $23.5 million over five years to help establish the Canadian Centre for Aging and Brain Health Innovation Centre at Baycrest Health Sciences, a world leader in cognitive neuroscience, and $25 million over five years to support the recently established Ontario Institute for Regenerative Medicine (OIRM).
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ChipCare closes oversubscribed $5 million series A financing

With lead investment from Puffin Partners, the Ontario, Canada-based company is taking lifesaving blood-testing technology to low- and middle-income countries

ChipCare device
ChipCare’s technology will provide simple-to-use, mobile, lab-quality blood testing for remote health settings. The University of Toronto start-up company’s first HIV-related test, targeted at linking people with HIV to appropriate treatments, is scheduled to hit the market in late 2016.

TORONTO, March 3, 2015 — ChipCare Corporation, a University of Toronto start-up company commercializing a handheld, blood-testing platform for HIV and other infectious and non-communicable diseases has closed a $5.045 million Series A financing to bring its first-generation product to market while further developing the platform’s next generation products.

The Wall Street Journal‘s Venture Capital Dispatch blog, Yonge Street Media, BetaKit and PEHub covered this announcement, along with the University of Toronto’s news site and a follow-up BetaKit article on how smartphones and start-ups are increasing access to healthcare. Information about past ChipCare  investment rounds and other company information is available in our ChipCare news archive.

Insufficient access in remote health settings to simple, accurate and affordable diagnostic tests makes it difficult to provide timely, evidence-based clinical care. Current technology within central laboratories cannot fulfill the existing need in remote health settings, including community level health facilities, remote communities, emergency departments, ICUs and doctors’ offices. The result is millions of preventable deaths from infectious and non-communicable diseases globally, reduced economic growth, and limited human development.

Chipcare CorporationChipCare’s technology will provide simple-to-use, mobile, lab-quality blood testing in remote health settings. The company’s first HIV-related test, targeted at linking people with HIV to appropriate treatments, is scheduled to hit the market in late 2016. The company is developing other products that leverage unique attributes of ChipCare’s technology.

Puffin Partners, LP, of Dallas, Texas led the financing round, which includes existing investors MaRS Innovation and Maple Leaf Angels, and new investors, including the Winfield Venture Group, Epic Capital, and additional Canadian and U.S. Angel investors.

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