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Thotra Receives National Post and Hindustan Times Coverage for Speech Transformation Technology

Thotra’s speech transformation technology to improve  comprehension in call centres and transcription services worldwide

Thotra logoOn October 11, 2013, The Hindustan Times covered a technology developed by UTEST start-up graduate Thotra (invented by Frank Rudzicz) for its speech-transformation software.

The article commends Thotra for recognizing the communications gap surrounding accents, hailing the technology as the solution to “put an end to all accent problems.”

On October 2, 2013, Thotra’s technology was also covered in the National Post:

The software, which filters out aspects of speech that can hinder comprehension, is put to the test by processing lines from Colin Firth in the movie The King’s Speech. The results showcase the potential of the software and how it can assist comprehension of accents.

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WaveCheck to Transform Chemotherapy Monitoring for Women with Breast Cancer

Indiegogo campaign to raise funds for North American clinical study during Breast Cancer Awareness Month; 12 artists donate 13 original works worth over $15,000 to support campaign

Toronto, Canada (October 9, 2013) — WaveCheck a painless, non-surgical clinical technique developed by a Sunnybrook Health Sciences Centre oncologist and a Ryerson University physicist and supported by MaRS Innovation — is poised to transform chemotherapy response monitoring for women with breast cancer.

Dr. Gregory Czarnota of Sunnybrook Health Sciences (left) and Professor Michael Kolios of Ryerson University, WaveCheck's inventors.
Dr. Gregory Czarnota of Sunnybrook Health Sciences (left) and Professor Michael Kolios of Ryerson University, WaveCheck’s inventors.

WaveCheck combines traditional ultrasound with new software to detect responses to chemotherapy in breast cancer tissues. By making better, more accurate information available about a woman’s response to her chemotherapy treatment in weeks rather than months, WaveCheck creates greater transparency through dialogue between a women and her doctors, empowering her to participate in discussions about whether a given chemotherapy treatment is effective.

Contribute to WaveCheck‘s Indiegogo campaign and help make this technology available to all women with breast cancer faster.

Media coverage: CTV News Channel, the Globe and Mail and Canadian Healthcare Technology have covered WaveCheck’s campaign.

Developed by Dr. Gregory Czarnota, chief of Radiation Oncology at Sunnybrook’s Odette Cancer Centre, and Michael C. Kolios, professor of Physics and Canada Research Chair in Biomedical Applications of Ultrasound at Ryerson, WaveCheck has been used in clinical studies with nearly 100 women receiving upfront, neoadjuvant chemotherapy to treat locally-advanced breast cancer. These results are published in two leading journals, Clinical Cancer Research and Translational Oncology.


In the Indiegogo campaign video, Czarnota, Kolios and three of the 100 women who participated in the first Sunnybrook study explain WaveCheck’s impact.

“The hard truth for women with breast cancer is that 60 to 70 per cent of chemotherapy treatments fail,” said Czarnota, who is also a senior scientist and director of cancer research at Sunnybrook Research Institute and assistant professor in the University of Toronto’s Departments of Radiation Oncology and Medical Biophysics within the Faculty of Medicine. “The 1.5 million women worldwide who will be diagnosed with breast cancer this year need to know that their chemotherapy is working as soon as possible. But this kind of treatment monitoring doesn’t currently exist in standard clinical practice. Instead, a woman’s tumour response is evaluated after she completes her chemotherapy treatment, which is typically a four- to six-month process.

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ChipCare, UTEST and MaRS Innovation profiled in Nature journal article on commercialization programs in Canada

Canadian commercialization and entrepreneurial programs helping scientists and researchers bring their products to market are the focus of a recent article in Nature Journal and on nature.com.

Posted online on October 2, 2013, the article explains how the Centres of Excellence in Commercialization and Research (CECR) programme, and specifically MaRS Innovation, develop research and put it into practice:

MaRS Innovation's commercialization process
MaRS Innovation’s commercialization process: Bridging the gap between brilliant research and successful start-up companies or licensable technologies.

“MARS Innovation and its sister organization MARS Discovery District are not-for-profit organizations that are tightly integrated in Canadian research commercialization. They are based in a heritage building that once belonged to the Toronto University Hospital, in the heart of the city’s ‘discovery district’ — the inner-city conglomeration of universities, institutes and hospitals which has a reputation as a research hotbed. “Here, all the different actors in the commercialization sphere come together in one space,” says Ilse Treurnicht, CEO of MARS Discovery District.

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VitalHub joins Box’s new ecosystem of electronic record healthcare applications

VitalHub Corp Logo: Patient information made easyVitalHub is building on its success in redefining how doctors access patient data by partnering with Box, which announced 13 new partnerships with companies, including VitalHub.

Together, their technology will work across web and mobile devices to help healthcare organizations work with, share and collaborate using information.

Invented at Toronto’s Mount Sinai Hospital in the IT Department, VitalHub was created to effectively manage patient data through a platform allowing clinicians to rapidly access comprehensive, relevant patient information gathered from multiple disparate clinical information systems.

The VitalHub Server platform sits on top of whatever clinical enterprise systems the hospital, community physician practice or healthcare organization already has in place.

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ChipCare’s handheld analyzer attracts one of Canada’s largest-ever healthcare angel investments

Device could significantly improve HIV diagnostics in developing world

Chipcare CorporationOTTAWA, September 16, 2013 — An innovative, handheld point-of-care analyzer, developed by ChipCare Corporation, has secured one of the largest ever angel investments in Canada’s healthcare sector.

Phase II financing has closed, with an investment of $2.05M to support ChipCare’s continuing development and commercialization over the next three years.

Media coverage: Biotechnology Focus, TechVibes, BetaKit, Healthrender, Crunchbase, Toronto Star and VentureLab.

The financing evolved through a uniquely collaborative funding model among Canadian social angel investors, including Maple Leaf Angels, MaRS Innovation and the University of Toronto (Connaught Fund), with special financing leadership from Grand Challenges Canada and the Government of Canada.

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Dr. Hofstein’s Op-Ed for The Hill-Times, “Biotechnology research: A knowledge economy”

This op-ed on Canadian biotechnology and the knowledge economy appeared in The Hill-Times (subscription required), Canada’s politics and government newsweekly, September 9:

Obesity, cancer, heart disease and stroke, diabetes, Parkinson’s disease, Alzheimer’s, or the more general stresses of an aging population: no matter which area of concern holds our collective gaze from moment to moment, improving health outcomes and healthcare is the No. 1 challenge for the world’s economy.

Canada has the holistic approach and translational research necessary to address health care’s pervasive challenges, with particular strengths in biotechnology.

In 2007, the Government of Canada made advancing translational research a top priority through the Science and Technology Strategy, with emphasis on cancer, metabolic disorders and, most recently, neurology, as part of the government’s response to the burdensome realities of neurodegenerative disorders.

Scientific research has made significant progress in unraveling the underlying causes of disorders such as Parkinson’s disease and Alzheimer’s disease, but translating these findings into useful clinical treatments is the key to attaining meaningful accomplishments. Only clinical treatment successes will alleviate pressure on the economy.

Transformational research is the essential first step in this process, but even more importantly, it needs to be put in the hands of those who can translate it into realistic and useful outcomes for patients in particular and society in general.

Thanks to research analytics that capture publications, citations, and other significant metrics, we know Canadian researchers punch above their weight, particularly in medical research. Canada’s challenge is not the quality or quantity of our research ideas but our ability to commercialize those ideas and translate them into market-ready products.

Aware of and concerned by this gap between fundamental basic research and useful patient, social, and economic outcomes, the Canadian government established the Centres of Excellence for Commercialization and Research (CECR) program in 2007. Part of the internationally-recognized Networks of Centres of Excellence suite of programs, the CECR program is a unique collaboration between the three federal granting agencies (the Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council, and Social Sciences and Humanities Research Council), along with Industry Canada, and Health Canada.

Designed to bridge the challenging gap between innovation and commercialization, the CECR program matches clusters of research expertise with the business community to share the knowledge and resources that bring innovations to market faster.

MaRS Innovation was among the first CECRs to be created in 2008, largely based on the founding belief of its members that Toronto is a fertile research land for precisely this kind of translational activity.

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Cellax profiled in SciBX; MaRS Innovation’s MSc PoP program cited in National Post supplement

CellaxThe Cellax technology was profiled in a recent issue of  SciBX (subscription necessary). MaRS Innovation is mentioned in the article as the technology’s commercialization agent.

Here’s an excerpt:

Ontario Institute for Cancer Research scientists have developed glycopolymer-conjugated docetaxel nanoparticles that outperform Abraxane in mouse models of breast cancer. The Ontario Institute for Cancer Research (OICR) is backing the program with $1.5 million to take it to the clinic. The expectation is that the product’s ability to target the tumor stroma rather than the tumor itself will differentiate it from Abraxane and other chemotherapeutic formulations.”

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Call for Applications: MaRS Innovation seeks applicants for early-stage MSc POP projects

Government of Ontario logoMaRS Innovation (MI) seeks applicants for the Medical Sciences Proof-of-Principle (MSc PoP) program, which supports early-stage medical science technologies and allows their founding teams to conduct crucial proof-of-principle work.

Through the two-year MSc POP program, MI will distribute funding awards to qualified applicants within its membership on behalf of the Ministry of Research and Innovation (MRI). Funds are available in $25,000 or $75,000 grants.

“At MaRS Innovation, the PoP program functions as a kind of internal Dragons’ Den,” says Dr. Raphael Hofstein, president and CEO of MaRS Innovation. “For three years, we’ve used a panel of industry leaders to hear pitches from the founding teams of the most promising technologies in our intellectual property pipeline. Based on their assessments, the strongest projects receive PoP funding to fuel their prototyping and other proof-of-principle work.”

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Whirlscape’s Minuum keyboard debuts at #2 on Google’s Top New Paid Apps list

Minuum #2 top paid new Android App on Google Play store
Minuum (icon second from left) is  the #2 Top Paid New Android App on the Google Play store. Graphic courtesy of Whirlscape Inc.

The Minuum keyboard, which made its public debut in the Google Play Store on August 21, 2013, has already reached #2 position in Google’s “Top New Paid Android Apps” list. The keyboard is the only non-game currently in that list’s top 10.

In the “Top Paid in Android Apps” general category, Minuum is already #9. The keyboard, made by Whirlscape Inc., has a four-star rating among users.

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