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Zucara Therapeutics

Phase 2 clinical trial targeting diabetes

TIAP portfolio company Zucara Therapeutics moves their lead program targeting diabetes into Phase II clinical trials. Read more here. Why this news is important: Zucara has achieved the development milestones required to secure the remaining funds available from its previously announcedUS$21 million Series A Financing. Zucara plans to file an investigational new drug (“IND”) application for a Phase 2 trial by year end, with initiation of first patient dosing expected in Q1 2023. ZT-01 has the potential to become the first therapeutic designed ... Read more

Highly Positive Results from PoC Phase 1b trial of ZT-01 – Type 1 Diabetes

Zucara Therapeutics announced highly positive results from its proof-of-concept Phase 1b trial of ZT-01 in people with Type 1 diabetes (“T1D”). Please see the press release here. Why this news is important: This trial confirms ZT-01’s mechanism of action in restoring glucagon release in patients with T1D. First-in-class ZT-01, meaningfully restored glucagon release in nearly 90% of treated patients compared to placebo (p<0.0001). This therapy has the potential to become the first therapeutic to prevent hypoglycemia in people with insulin-dependent diabetes. Positive results from this trial will enable Zucara to further evaluate ZT-01 in a multi-center Phase 2 ... Read more

Funding for Zucara Therapeutics Expansion Into ZT-01 Development Program to Type 2 Diabetes

November 2, 2020: Zucara Therapeutics Inc., a diabetes life sciences startup funded by TIAP and adMare BioInnovations,  announced today that it has received funding from NRC IRAP and MITAS for its expansion into the development of ZT-01, a somatostatin receptor 2 antagonist (“SSTR2a”), to Type 2 Diabetes (“T2D”). Red more here: https://bit.ly/34QRAn6 Read more

Zucara Therapeutics Announces US$21M Series A Financing

– Proceeds to Fund Development of ZT-01 Through Phase 2 Clinical Trials – – Series A Financing led by the Perceptive Xontogeny Venture Fund  – TORONTO, March 31, 2020 (GLOBE NEWSWIRE) -- Zucara Therapeutics Inc., a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has closed a US$21 million Series A Financing led by the Perceptive Xontogeny Venture Fund (“PXV Fund”). The proceeds from the financing will fund Phase 1 and ... Read more